… This kinase is activated by ischemia and short-term hibernation. We hypothesized that p38
MAPK activation may contribute to the contractile deficit that characterizes low-flow ischemia. …

… This might be explained if preconditioning reduced the activation of p38 MAPK α/β during …
, there was a significant increase in p38 MAPK activity compared with control, aerobic perfused …

… Methods: Sixty-five enflurane-anesthetized pigs underwent 90 min low-flow ischemia and
120 min … We also did not assess p38 MAP kinase activity in vivo using an in gel assay. Since …

… occurs during a 3×5min preconditioning protocol: the activation was maximal during the
first episode, becoming progressively lower during the second and third episodes. …

… Aortic flow was drastically reduced during reperfusion in both non-adapted and adapted …
kinase phosphorylation and p38 MAP kinase activity. To confirm NFκB binding activity with p65, …

… transcription factors, thereby aggravating the myocardial ischemia-reperfusion injury13.
Therefore, the activity of the p38 MAPK pathway can be reduced via appropriate intervention to …

… -ischemic JNK and p38 (but not ERK1/2) activation was markedly reduced in a model of
kidney ischemic … Figure 8JNK kinase activity and phosphorylation of JNK , p38, and ERK1/2 in …

… We have shown here that the increased enzyme activity or immunoreactivity of p38 MAPK, …
Blockade of the p38 pathway contributed to reduced injury in cerebral tissue, which led to …

… hearts, and the AMPK activity of TAB1/AMPK complexes was similar in ischemic mkk3 −/−
and … We found that the p38 MAPK inhibitor SB203580 reduced AICAR-stimulated glucose …

… Tissue flow was calculated as a ratio between activity (cpm/g… sensitive p38 MAP kinase is
partially responsible for ischemia-… of the small caliber of the vessels. Therefore, the only way for …