[HTML][HTML] A randomized phase II study comparing erlotinib versus erlotinib with alternating chemotherapy in relapsed non-small-cell lung cancer patients: the NVALT-10 …

JG Aerts, H Codrington, NAG Lankheet, S Burgers… - Annals of oncology, 2013 - Elsevier
Erlotinib was administered daily at the same time each day … , erlotinib was continued daily
until intolerable toxic effect or … monotherapy with combination chemotherapy and erlotinib, in …

[HTML][HTML] Efficacy and safety of erlotinib combined with bevacizumab in the treatment of non-small cell lung cancer: A systematic review and meta-analysis

K Zhou, S Zhao, W Guo, L Ding - Medicine, 2020 - journals.lww.com
… shown high efficacy and low toxicity for NSCLC. In particular, combining erlotinib with the
VEGF … Our meta-analysis indicates that compared with monotherapy, erlotinib+bevacizumab …

Erlotinib

M Steins, M Thomas, M Geißler - Small molecules in oncology, 2018 - Springer
… Its clinical applications, evidence-based efficacy and toxicity as well as … erlotinib combination
therapies (mainly with targeted drugs) randomised against erlotinib as monotherapy has …

Acute fatal liver toxicity under erlotinib

S Schacher-Kaufmann, M Pless - Case reports in oncology, 2010 - karger.com
… A direct link between erlotinib monotherapy and coagulopathy seems less likely; there are
no reports in the literature to support such a hypothesis. Two cases of patients with pancreatic …

Erlotinib plus bevacizumab versus erlotinib alone in patients with EGFR-positive advanced non-squamous non-small-cell lung cancer (NEJ026): interim analysis of an …

H Saito, T Fukuhara, N Furuya, K Watanabe… - The Lancet …, 2019 - thelancet.com
… established the activity and manageable toxicity of erlotinib plus bevacizumab in … and
erlotinib was compared with erlotinib monotherapy to evaluate activity in patients with non-small-…

EGFR inhibitor erlotinib plus monoclonal antibody versus erlotinib alone for first-line treatment of advanced non-small cell lung carcinoma: A systematic review and …

M Liu, K Xiao, L Yang - International Immunopharmacology, 2023 - Elsevier
… G3-5 toxicities were rash and diarrhea in studies using both erlotinib monotherapy and
combination therapy. Furthermore, the results showed that, when using erlotinib plus mAbs, the …

A spectrum of cutaneous toxicities from erlotinib may be a robust clinical marker for non-small-cell lung therapy: A case report and literature review

F Jin, H Zhu, L Kong, J Yu - OncoTargets and therapy, 2015 - Taylor & Francis
… the correlation between a spectrum of cutaneous toxicities from EGFR inhibition and drug …
using erlotinib monotherapy, who experienced a spectrum of cutaneous toxicities, including …

A first-in-human phase I study of a bivalent MET antibody, emibetuzumab (LY2875358), as monotherapy and in combination with erlotinib in advanced cancer

LS Rosen, JW Goldman, AP Algazi, PK Turner… - Clinical Cancer …, 2017 - AACR
… 15 of a 28-day cycle as monotherapy (Part A) or in combination with erlotinib at the FDA-…
monotherapy or in combination with erlotinib. Secondary objectives included safety and toxicity

Erlotinib in the treatment of recurrent or metastatic cutaneous squamous cell carcinoma: a single‐arm phase 2 clinical trial

KA Gold, MS Kies, WN William Jr, FM Johnson… - Cancer, 2018 - Wiley Online Library
… and was associated with expected toxicities. However, only a … daily in patients with non–small
cell lung cancer not selected … establish the efficacy of erlotinib monotherapy with a phase 2 …

Upfront gefitinib/erlotinib treatment followed by concomitant radiotherapy for advanced lung cancer: a mono-institutional experience

CC Chang, KH Chi, SJ Kao, PS Hsu, YW Tsang… - Lung Cancer, 2011 - Elsevier
… The dose of TKI was reduced to 1 tablet every other day because of toxicity or economic …
IV NSqCLC with a clinical benefit from TKI monotherapy. Our data may aid expansion of the …