[HTML][HTML] Lipoprotein (a) beyond the kringle IV repeat polymorphism: the complexity of genetic variation in the LPA gene
S Coassin, F Kronenberg - Atherosclerosis, 2022 - Elsevier
… Genetic variants of interest in the LPA gene region.This table summarizes information about
selected variants that have been either extensively discussed in the literature or that present …
selected variants that have been either extensively discussed in the literature or that present …
LPA Gene, Ethnicity, and Cardiovascular Events
SR Lee, A Prasad, YS Choi, C Xing, P Clopton… - Circulation, 2017 - Am Heart Assoc
… Lipoprotein(a) genetic variants associated with coronary and peripheral vascular disease
but not with stroke risk in the Heart Protection Study.Circ Cardiovasc Genet. 2011; 4:68–73. …
but not with stroke risk in the Heart Protection Study.Circ Cardiovasc Genet. 2011; 4:68–73. …
[HTML][HTML] Prediction of cardiovascular risk by Lp(a) concentrations or genetic variants within the LPA gene region
F Kronenberg - Clinical Research in Cardiology Supplements, 2019 - Springer
… we observed 2001 SNPs in the wider LPA gene region which were significantly associated
with … From all 49 genetic variants that were shown to be independently associated with Lp(a) …
with … From all 49 genetic variants that were shown to be independently associated with Lp(a) …
Genetic Variation in LPAL2, LPA, and PLG Predicts Plasma Lipoprotein(a) Level and Carotid Artery Disease Risk
J Ronald, R Rajagopalan, F Cerrato, AS Nord… - Stroke, 2011 - Am Heart Assoc
… The relationship between genetic variation in the LPA gene region and CAAD risk remains
… between LPA polymorphisms and coronary artery disease, 22 we evaluated the role of LPA …
… between LPA polymorphisms and coronary artery disease, 22 we evaluated the role of LPA …
Comprehensive Analysis of Genomic Variation in the LPA Locus and Its Relationship to Plasma Lipoprotein(a) in South Asians, Chinese, and European Caucasians
… under the control of genetic variation in the LPA gene due to the cumulative effects of multiple
rare and common genetic variants. A common copy number variation in LPA, created by a …
rare and common genetic variants. A common copy number variation in LPA, created by a …
Genetic variation in LPA, calcific aortic valve stenosis in patients undergoing cardiac surgery, and familial risk of aortic valve microcalcification
… In this study, we found that genetic variation at the LPA locus associated with higher Lp(a)
levels was strongly associated with CAVS risk in patients undergoing cardiac surgery. …
levels was strongly associated with CAVS risk in patients undergoing cardiac surgery. …
Prevalence and influence of LPA gene variants and isoform size on the Lp (a)-lowering effect of pelacarsen
E Karwatowska-Prokopczuk, N Clouet-Foraison, S Xia… - Atherosclerosis, 2021 - Elsevier
… Patients have been recruited according to various Lp(a) thresholds, but the prevalence of
LPA genetic variants and their effect on efficacy of these ASOs are not well described. …
LPA genetic variants and their effect on efficacy of these ASOs are not well described. …
Genetic variants associated with Lp (a) lipoprotein level and coronary disease
R Clarke, JF Peden, JC Hopewell… - … England Journal of …, 2009 - Mass Medical Soc
… First, we examined genetic associations in coronary … genes selected for their putative
relevance to cardiovascular disease. Second, we assessed the associations of LPA gene variants …
relevance to cardiovascular disease. Second, we assessed the associations of LPA gene variants …
… between lipoprotein (a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic …
S Zewinger, ME Kleber, V Tragante… - The lancet Diabetes & …, 2017 - thelancet.com
… Whether lipoprotein(a) concentrations or LPA genetic variants predict long-term mortality in
… , lipoprotein(a) concentrations and genetic variants showed no associations with mortality. …
… , lipoprotein(a) concentrations and genetic variants showed no associations with mortality. …
Genetic variants in the apolipoprotein (a) gene and coronary heart disease
Y Li, MM Luke, D Shiffman, JJ Devlin - … : Cardiovascular Genetics, 2011 - Am Heart Assoc
… determined, 47 a comprehensive analysis of the LPA … Genetic variation in the LPA locus
explains a substantial portion of the variation in Lp(a) levels 47 ; however, the genetic variants …
explains a substantial portion of the variation in Lp(a) levels 47 ; however, the genetic variants …
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