[HTML][HTML] Lipoprotein (a) beyond the kringle IV repeat polymorphism: the complexity of genetic variation in the LPA gene

S Coassin, F Kronenberg - Atherosclerosis, 2022 - Elsevier
Genetic variants of interest in the LPA gene region.This table summarizes information about
selected variants that have been either extensively discussed in the literature or that present …

LPA Gene, Ethnicity, and Cardiovascular Events

SR Lee, A Prasad, YS Choi, C Xing, P Clopton… - Circulation, 2017 - Am Heart Assoc
… Lipoprotein(a) genetic variants associated with coronary and peripheral vascular disease
but not with stroke risk in the Heart Protection Study.Circ Cardiovasc Genet. 2011; 4:68–73. …

[HTML][HTML] Prediction of cardiovascular risk by Lp(a) concentrations or genetic variants within the LPA gene region

F Kronenberg - Clinical Research in Cardiology Supplements, 2019 - Springer
… we observed 2001 SNPs in the wider LPA gene region which were significantly associated
with … From all 49 genetic variants that were shown to be independently associated with Lp(a) …

Genetic Variation in LPAL2, LPA, and PLG Predicts Plasma Lipoprotein(a) Level and Carotid Artery Disease Risk

J Ronald, R Rajagopalan, F Cerrato, AS Nord… - Stroke, 2011 - Am Heart Assoc
… The relationship between genetic variation in the LPA gene region and CAAD risk remains
… between LPA polymorphisms and coronary artery disease, 22 we evaluated the role of LPA

Comprehensive Analysis of Genomic Variation in the LPA Locus and Its Relationship to Plasma Lipoprotein(a) in South Asians, Chinese, and European Caucasians

MB Lanktree, SS Anand, S Yusuf… - … Cardiovascular Genetics, 2010 - Am Heart Assoc
… under the control of genetic variation in the LPA gene due to the cumulative effects of multiple
rare and common genetic variants. A common copy number variation in LPA, created by a …

Genetic variation in LPA, calcific aortic valve stenosis in patients undergoing cardiac surgery, and familial risk of aortic valve microcalcification

N Perrot, S Thériault, C Dina, HY Chen… - JAMA …, 2019 - jamanetwork.com
… In this study, we found that genetic variation at the LPA locus associated with higher Lp(a)
levels was strongly associated with CAVS risk in patients undergoing cardiac surgery. …

Prevalence and influence of LPA gene variants and isoform size on the Lp (a)-lowering effect of pelacarsen

E Karwatowska-Prokopczuk, N Clouet-Foraison, S Xia… - Atherosclerosis, 2021 - Elsevier
… Patients have been recruited according to various Lp(a) thresholds, but the prevalence of
LPA genetic variants and their effect on efficacy of these ASOs are not well described. …

Genetic variants associated with Lp (a) lipoprotein level and coronary disease

R Clarke, JF Peden, JC Hopewell… - … England Journal of …, 2009 - Mass Medical Soc
… First, we examined genetic associations in coronary … genes selected for their putative
relevance to cardiovascular disease. Second, we assessed the associations of LPA gene variants

… between lipoprotein (a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic …

S Zewinger, ME Kleber, V Tragante… - The lancet Diabetes & …, 2017 - thelancet.com
… Whether lipoprotein(a) concentrations or LPA genetic variants predict long-term mortality in
… , lipoprotein(a) concentrations and genetic variants showed no associations with mortality. …

Genetic variants in the apolipoprotein (a) gene and coronary heart disease

Y Li, MM Luke, D Shiffman, JJ Devlin - … : Cardiovascular Genetics, 2011 - Am Heart Assoc
… determined, 47 a comprehensive analysis of the LPAGenetic variation in the LPA locus
explains a substantial portion of the variation in Lp(a) levels 47 ; however, the genetic variants