Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissues

MF Shamji, LA Setton, W Jarvis, S So… - Arthritis & …, 2010 - Wiley Online Library
… as representing degenerative disc disease or herniated IVD (Table 1), with no differences
in BMI or sex distribution between pathology groups. Patients with degenerative disc disease

Correlational analysis of chemokine and inflammatory cytokine expression in the intervertebral disc and blood in patients with lumbar disc disease

A Hiyama, K Suyama, D Sakai… - Journal of …, 2022 - Wiley Online Library
inflammatory cytokine gene expression in … inflammatory cytokine and chemokine expression
in human IVD tissues and WB samples from patients with lumbar degenerative disc disease

Role of cytokines in intervertebral disc degeneration: pain and disc content

MV Risbud, IM Shapiro - Nature Reviews Rheumatology, 2014 - nature.com
inflammatory cytokines during each of the individual phases of degenerative disc disease, …
the high levels of inflammatory cytokines and the dysregulated expression of genes of the …

mRNA expression of cytokines and chemokines in herniated lumbar intervertebral discs

SH Ahn, YW Cho, MW Ahn, SH Jang, YK Sohn, HS Kim - Spine, 2002 - journals.lww.com
… to downregulate the production of multiple proinflammatory cytokines. However, little has
been reported concerning the kinds and roles of cytokines involved in lumbar disc herniations. …

Inflammatory cytokines released from the facet joint tissue in degenerative lumbar spinal disorders

A Igarashi, S Kikuchi, S Konno, K Olmarker - Spine, 2004 - journals.lww.com
… The aim of this study was to quantify inflammatory cytokines in the facet joint tissue in
degenerative lumbar spinal disorders and to relate them to the clinical symptoms. …

Low back pain scores correlate with the cytokine mRNA level in lumbar disc biopsies: a study of inflammatory markers in patients undergoing lumbar spinal fusion

SS Aripaka, R Bech-Azeddine, LM Jørgensen… - European Spine …, 2021 - Springer
… behind pain in degenerative disc disease (DDD) and chronic low back pain (LBP) patients
… the expression of inflammatory cytokines in the lumbar disc and disability and low back pain

Comparison of growth factor and cytokine expression in patients with degenerated disc disease and herniated nucleus pulposus

S Lee, CS Moon, D Sul, J Lee, M Bae, Y Hong… - Clinical …, 2009 - Elsevier
… In general, there are two primary causes of LBP, degenerative disc disease (DDD) and disc
… Many studies have been conducted to investigate the expression of inflammatory cytokines, …

[HTML][HTML] Serum levels of the proinflammatory cytokine interleukin-6 vary based on diagnoses in individuals with lumbar intervertebral disc diseases

KT Weber, DO Alipui, CP Sison, O Bloom… - Arthritis research & …, 2016 - Springer
proinflammatory cytokines in the absence of inflammatory cells, supporting the hypothesis that
disc-… IL-6 expression levels increase in response to IVD injury in preclinical models [65, 66]…

[PDF][PDF] Catabolic cytokine expressions in patients with degenerative disc disease

S Akyol, BS Eraslan, H Etyemez… - Turkish …, 2010 - turkishneurosurgery.org.tr
lumbar disc histogen cells can be a source of NK, CD8 cytotoxic cells, proand anti-inflammatory
cytokines in degenerative … of IL-I2 expression may be different in degenerated discs; the …

[HTML][HTML] Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1β and TNFα expression profile

CL Le Maitre, JA Hoyland, AJ Freemont - Arthritis research & therapy, 2007 - Springer
… The inhibition of IL-1 driven processes, leading to disc degenerationdisc degeneration at
an early stage (such as degeneration induced at adjacent levels following spinal fusion or disc