Molecular genetics of lung cancer

Y Sekido, KM Fong, JD Minna - Annual review of medicine, 2003 - annualreviews.org
… –small cell lung cancer (NSCLC), which includes adenocarcinoma,… in current molecular
genetic research for human lung cancer.… We also discuss how genetic and epigenetic analysis of …

[HTML][HTML] Comprehensive molecular profiling of lung adenocarcinoma

Cancer Genome Atlas Research Network - Nature, 2014 - ncbi.nlm.nih.gov
Adenocarcinoma of the lung is the leading cause of cancer death worldwide. Here we report
molecular profiling of 230 resected lung adenocarcinomas … significantly mutated genes from …

Molecular genetics of small cell lung carcinoma

II Wistuba, AF Gazdar, JD Minna - Seminars in oncology, 2001 - Elsevier
… distinct genetic pathways in the major subtypes of lung cancers (… molecular genetic
abnormalities that are involved in lung … the molecular basis of lung cancers should allow …

[HTML][HTML] Lung adenocarcinoma: from molecular basis to genome-guided therapy and immunotherapy

R Chalela, V Curull, C Enriquez, L Pijuan… - Journal of thoracic …, 2017 - ncbi.nlm.nih.gov
… Of them, three major loci strongly relate to lung cancer: these are 15q25 of the genes … of
polymorphism in two genes, those encoding TERT and CLPTM1L, with lung cancer, indifferently …

Molecular genetic testing for lung adenocarcinomas: a practical approach to clinically relevant mutations and translocations

S Dacic - Journal of Clinical Pathology, 2013 - jcp.bmj.com
… advanced lung adenocarcinoma has raised hope that a genotype-driven targeted treatment
approach to lung cancer will improve survival and quality of life of patients with lung cancer.1…

Molecular genetics of lung cancer in people who have never smoked

J Subramanian, R Govindan - The lancet oncology, 2008 - thelancet.com
molecular genetics of lung cancer in never smokers and identify the specific differences from
tobacco-associated lung … Patterns of allelic loss differ in lung adenocarcinomas of smokers …

ALK gene rearranged lung adenocarcinomas: molecular genetics and morphology in cohort of patients from North India

A Bal, N Singh, P Agarwal, A Das, D Behera - Apmis, 2016 - Wiley Online Library
… ALK gene rearrangement in the lung adenocarcinomas is the second most common (… lung
adenocarcinomas from North India are lacking. A total of 240 cases of lung adenocarcinoma

Alk-rearranged lung adenocarcinoma: From molecular genetics to therapeutic targeting

U Testa, G Castelli, E Pelosi - Tumori Journal, 2024 - journals.sagepub.com
… cell lung cancer (NSCLC) accounts for about 85% of lung cancers; … lung adenocarcinoma
(LUAD) (40-50% of lung cancers) and lung squamous cell carcinoma (LUSC) (25-30% of lung

Molecular genetic abnormalities in the pathogenesis of human lung cancer

E Forgacs, S Zöchbauer-Müller, E Oláh… - Pathology Oncology …, 2001 - Springer
… If we can detect some of these genetic alterations in preneoplastic … molecular abnormalities
in lung cancer pathogenesis including altered expression and function of oncogenes, loss of …

[HTML][HTML] Molecular biology of lung cancer

WA Cooper, DCL Lam, SA O'Toole… - Journal of thoracic …, 2013 - ncbi.nlm.nih.gov
… of the molecular biology that underpins lung cancer in recent … the diagnosis and treatment
of lung adenocarcinomas (ADC) … of molecular alterations at multiple levels (genetic, epigenetic…