Chemotherapy resistance in lung cancer

ES Kim - Lung Cancer and Personalized Medicine: Current …, 2016 - Springer
… for both non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). However,
chemotherapy resistance limits our ability to effectively treat advanced lung cancer. Some …

Mechanisms of resistance to chemotherapy in non-small cell lung cancer

HY Min, HY Lee - Archives of pharmacal research, 2021 - Springer
Non-small cell lung cancer (NSCLC), which represents 80–85% of lung cancer cases, is
one of the leading causes of human death worldwide. The majority of patients undergo an …

[HTML][HTML] Chemotherapy resistance and oncogene expression in non–small cell lung cancer

TA d'Amato, RJ Landreneau, W Ricketts… - The Journal of thoracic …, 2007 - Elsevier
… Multi-drug chemotherapy resistance in non–small cell lung cancer tumor cultures is common,
and associations between molecular markers and in vitro chemotherapy resistance are …

Basic mechanisms of therapeutic resistance to radiation and chemotherapy in lung cancer

H Willers, CG Azzoli, WL Santivasi, F Xia - The Cancer Journal, 2013 - journals.lww.com
… of human cancers including lung cancer. Defects … lung tumors to radiation therapy. Here,
we will review clinically relevant mechanisms affecting resistance and sensitivity of lung cancer

[HTML][HTML] LUBAC determines chemotherapy resistance in squamous cell lung cancer

EJ Ruiz, ME Diefenbacher, JK Nelson… - The Journal of …, 2019 - ncbi.nlm.nih.gov
… the most common lung cancer subtypes. … resistance to cisplatin-based chemotherapy, and
we identified LUBAC-mediated NF-κB signaling as a determinant of chemotherapy resistance

Chemotherapy resistance molecular mechanism in small cell lung cancer

J Zhou, Z Li, J Li, B Gao, W Song - Current Molecular Medicine, 2019 - ingentaconnect.com
… on drug resistance in small cell lung cancer chemotherapy. Asian Pac J Cancer Prev 2012;
… in the mediation of chemotherapy resistance in human small cell lung cancer cell lines. Int J …

TLR7 promotes tumor progression, chemotherapy resistance, and poor clinical outcomes in non–small cell lung cancer

S Chatterjee, L Crozet, D Damotte, K Iribarren… - Cancer research, 2014 - AACR
… associated with resistance to neoadjuvant chemotherapy and poor clinical outcomes. Our
findings delineate a crucial role for TLR7 in lung cancer physiopathology. Cancer Res; 74(18); …

Prevalence of in vitro extreme chemotherapy resistance in resected nonsmall-cell lung cancer

TA d'Amato, RJ Landreneau, RJ McKenna… - The Annals of thoracic …, 2006 - Elsevier
… ; however, little is known of the prevalence of extreme chemotherapy drug resistance for …
chemotherapy toxicity. This study describes the prevalence of in vitro chemotherapy resistance

Investigation of the role of p53 in chemotherapy resistance of lung cancer cell lines

L Breen, M Heenan, V Amberger-Murphy… - Anticancer …, 2007 - ar.iiarjournals.org
… a number of lung cancer cell lines with different p53 status were transfected with wild-type
p53 in order to determine the role of p53 in the development of drug resistance. Many groups …

Rev7 loss alters cisplatin response and increases drug efficacy in chemotherapy-resistant lung cancer

FM Vassel, K Bian, GC Walker… - Proceedings of the …, 2020 - National Acad Sciences
… shown to improve cisplatin chemotherapy by suppressing tumor … potentiates cisplatin
chemotherapy in a lung cancer model. … Rev7 is an attractive strategy to improve chemotherapy. …