Pemetrexed combination therapy in the treatment of non–small cell lung cancer

R Rosell, L Crinó - Seminars in oncology, 2002 - Elsevier
… In summary, pemetrexed has emerged as a promising new … combinations has remained
almost purely empirical,1, 2 and anticancer drug combinations in non–small cell lung cancer (…

Pemetrexed with platinum combination as a backbone for targeted therapy in non–small-cell lung cancer

TE Stinchcombe, H Borghaei, SS Barker, JA Treat… - Clinical Lung Cancer, 2016 - Elsevier
… Thus, the pemetrexed–platinum backbone provides an attractive option for combination with
… of pemetrexed–platinum as a backbone for combination with targeted therapies for NSCLC. …

Role of pemetrexed and platinums combination in patients with non-small cell lung cancer

M Chen, W Shao, J He, D Wang - Current Drug Targets, 2010 - ingentaconnect.com
… of advanced non-small cell lung cancer (NSCLC), the … cytotoxic agent, pemetrexed, and its
combination with platinums … ) to pemetrexed/platinum in NSCLC, and the role of pemetrexed/…

Phase II study of pemetrexed in combination with carboplatin in the first‐line treatment of advanced nonsmall cell lung cancer

RG Zinner, FV Fossella, GW Gladish… - Cancer …, 2005 - Wiley Online Library
pemetrexed and its activity against a wide range of solid tumors.7 Another early Phase I
study established the safety of pemetrexed in combination … from Australia, pemetrexed as first-…

Pemetrexed for the treatment of non-small-cell lung cancer

C Manegold, G Schmid-Bindert… - Expert Review of …, 2009 - Taylor & Francis
… of pemetrexed in … of lung cancer, allowing physicians to tailor therapies to the individual
patient. Ongoing trials aim to establish the place of pemetrexed in maintenance, in combination

Pemetrexed combined with paclitaxel in patients with advanced or metastatic non-small-cell lung cancer: a phase I-II trial

GP Stathopoulos, J Dimitroulis, M Toubis, C Katis… - Lung Cancer, 2007 - Elsevier
Pemetrexed, a novel multi-targeted agent established for the treatment of mesothelioma, …
-cell lung cancer (NSCLC). In the present trial we investigated pemetrexed in combination with …

Pemetrexed monotherapy versus pemetrexed plus platinum combination as second-line treatment for advanced non-small cell lung cancer

Y Zhang, Z Chen, S Lu - Chinese medical journal, 2009 - mednexus.org
… Inthisreport,wecomparetheefectsandtoxicities in advanced NSCLC patients treated with
pemetrexed monotherapyversuspemetrexedplusplatinum combination agentso as co provide a …

Comparison of pemetrexed plus cisplatin with other first-line doublets in advanced non-small cell lung cancer (NSCLC): a combined analysis of three phase 3 trials

J Treat, GV Scagliotti, G Peng, MJ Monberg… - Lung cancer, 2012 - Elsevier
… The primary objective of the current combined analysis of three large phase 3 trials was
to determine the comparability (overall and by histology) of pemetrexed–cisplatin with other …

[HTML][HTML] Review of the pemetrexed and gemcitabine combination in patients with advanced-stage non-small cell lung cancer

C Monnerat, T Le Chevalier - Annals of Oncology, 2006 - Elsevier
… Adjei, AA Gemcitabine and pemetrexed disodium combinations in vitro and in vivo Lung
Cancer … Dark, GG Pemetrexed combined with oxaliplatin or carboplatin as first-line treatment in …

Pemetrexed for the treatment of non-small cell lung cancer

C Genova, E Rijavec, A Truini, S Coco… - Expert opinion on …, 2013 - Taylor & Francis
… the purpose of investigating the possible advantage of combining pemetrexed with other
agents. Combinations of pemetrexed and cisplatin or carboplatin in previously treated NSCLC …