Linking the generation of DNA adducts to lung cancer

M Ceppi, A Munnia, F Cellai, M Bruzzone, MEM Peluso - Toxicology, 2017 - Elsevier
… the relationship among DNA adducts and lung cancer risk in … of adducts were measured
in bronchial cells of lung cancer … -analysis of bronchial adducts and lung cancer so far, with …

DNA adducts and lung cancer risk: a prospective study

M Peluso, A Munnia, G Hoek, M Krzyzanowski… - Cancer research, 2005 - AACR
… that the levels of leukocyte DNA adducts could predict lung cancer in healthy never-smokers …
of DNA damage were approximately twice more likely to be diagnosed with lung cancer

DNA adduct level in lung tissue may act as a risk biomarker of lung cancer

YW Cheng, CY Chen, P Lin, CP Chen… - … Journal of Cancer, 2000 - Elsevier
… reflect the degree of DNA damage in the target organ of the lung and thus cannot properly …
the DNA adduct levels in lung tissue from lung cancer patients and non-cancer controls using …

Gender difference in DNA adduct levels among nonsmoking lung cancer patients

YW Cheng, LL Hsieh, PP Lin, CP Chen… - Environmental and …, 2001 - Wiley Online Library
… in lung tissues of study subjects. Our data showed that the DNA adduct levels of lung cancer
… high risk of lung cancer because of high susceptibility to DNA adduct formation derived from …

Repair of tobacco carcinogen-induced DNA adducts and lung cancer risk: a molecular epidemiologic study

Q Wei, L Cheng, CI Amos, LE Wang… - … the National Cancer …, 2000 - academic.oup.com
… low DRC in lung cancer patients are consistent with results from recent studies of DNA
adducts. A lower DRC would result in higher levels of tobacco-related DNA adducts. For example, …

Polycyclic aromatic hydrocarbon-DNA adducts in lung tissue from lung cancer patients

FJ Van Schooten, MJX Hillebrand… - …, 1990 - academic.oup.com
… between DNA adduct levels in human lung and … of adducts formed by aromatic compounds.
In this report we present evidence that a major DNA adduct in lung tissue from lung cancer

Oral cell DNA adducts as potential biomarkers for lung cancer susceptibility in cigarette smokers

SS Hecht - Chemical research in toxicology, 2017 - ACS Publications
… , we discuss DNA adducts in human oral cells, quantified by mass spectrometry, as
potentially useful biomarkers for lung cancer risk. Our main hypothesis is that these DNA adduct

Smoking-related DNA adducts as potential diagnostic markers of lung cancer: new perspectives

ES Grigoryeva, DA Kokova, AN Gratchev… - Experimental …, 2015 - irbis-nbuv.gov.ua
… the risk forlung cancer. This review is devoted to analysis of the role of DNA adducts in
lung carcinogenesis in order to demonstrate their usefulness as cancer associated markers. …

Association between carcinogen-DNA adducts in white blood cells and lung cancer risk in the physicians health study

D Tang, DH Phillips, M Stampfer, LVA Mooney, Y Hsu… - Cancer research, 2001 - AACR
lung cancer. In this study, we have evaluated whether PAH- and other aromatic-DNA adducts
… risk among those who were subsequently classified as lung cancer cases (n = 89) or as …

Methyl DNA phosphate adduct formation in lung tumor tissue and adjacent normal tissue of lung cancer patients

B Ma, PW Villalta, JB Hochalter, I Stepanov… - …, 2019 - academic.oup.com
… methyl DNA phosphate adducts in both lung tumor tissue and the adjacent normal tissue of
patients with lung cancer… status at the time of lung cancer surgery by measurement of urinary …