[HTML][HTML] A unified dose response relationship to predict high dose fractionation response in the lung cancer stereotactic body radiation therapy

TS Kehwar, KL Chopra, DV Rai - Journal of Medical Physics, 2017 - journals.lww.com
dose of radiation is delivered in one or few fractions with high conformity to an extra-cranial
body targets.[ 15 16 17 18 ] Use of large dose fractions … sensitivity of the tumor cells.[ 19 ] The …

Modeling the cellular response of lung cancer to radiation therapy for a broad range of fractionation schedules

J Jeong, JH Oh, JJ Sonke, J Belderbos, JD Bradley… - Clinical Cancer …, 2017 - AACR
… accurately predicts tumor-response likelihood for a broad range of fractionation regimens
for lung cancer, a result that has not previously been achieved. This cellular response model, …

[HTML][HTML] Optimizing radiation dose and fractionation for the definitive treatment of locally advanced non-small cell lung cancer

MC Roach, JD Bradley, CG Robinson - Journal of thoracic disease, 2018 - ncbi.nlm.nih.gov
… Resection after concurrent chemoradiation therapy show that this combination of radiation
and chemotherapy only leads to complete response in 35–45% of patients (6,7). This review …

Doseresponse for stereotactic body radiotherapy in early-stage non–small-cell lung cancer

JR Olsen, CG Robinson, I El Naqa, KM Creach… - International Journal of …, 2011 - Elsevier
… We have used a consistent lung SBRT technique and dose fractionation schedule since …
and dose prescription has permitted outcome comparison among the three fractionation

[HTML][HTML] Dose and fractionation schedules in radiotherapy for non-small cell lung cancer

L Kepka, J Socha - Translational Lung Cancer Research, 2021 - ncbi.nlm.nih.gov
… damage to late-responding tissues of great vessels, bronchi, heart, and esophagus. The
issues of modified fractionation and total dose escalation will be discussed in the current review. …

Optimal fractionation in radiotherapy for non-small cell lung cancer–a modelling approach

E Lindblom, A Dasu, I Toma-Dasu - Acta Oncologica, 2015 - Taylor & Francis
Dose-response curves for various fractionation schedules with and without fast reoxygenation
Dose fractionation, dose rate and iso-effect relationships for normal tissue responses. Int J …

The impact of radiation dose and fractionation on outcomes for limited-stage small-cell lung cancer

N Tomita, T Kodaira, T Hida, H Tachibana… - International Journal of …, 2010 - Elsevier
… In our study, the comparison of overall, progression-free, and local control survival rates and
the rate of complete response suggested that TRT administered with a total dose of <54 Gy …

Steep doseresponse relationship for stage I non–small-cell lung cancer using hypofractionated high-dose irradiation by real-time tumor-tracking radiotherapy

R Onimaru, M Fujino, K Yamazaki, Y Onodera… - International Journal of …, 2008 - Elsevier
… The dose fractionation schedule was 40 or 48 Gy in four fractions within 1 week. The dose
was prescribed at the center of the planning target volume, giving more than an 80% dose at …

Tumor control and toxicity for common stereotactic body radiation therapy dose-fractionation regimens in stage I non-small cell lung cancer

KL Stephans, NM Woody, CA Reddy, M Varley… - International Journal of …, 2018 - Elsevier
… noted the possibility of a distinct doseresponse for T1 versus T2 tumors, … doseresponse
curve, the reporting of outcomes of individual discrete and commonly used dose fractionation

Dose escalation for non-small cell lung cancer: analysis and modelling of published literature

M Partridge, M Ramos, A Sardaro, M Brada - Radiotherapy and Oncology, 2011 - Elsevier
… choice of dose fractionation schedule. Based on the available data showing a sigmoid
doseresponse relationship it is hypothesised that the maximum gain is likely to be achieved with …