… This review summarizes the current knowledge of EGFR TK domain mutations and the role
… importance of EGFR mutation status in the selection of patients for EGFR TKI therapy. EGFR …

… lung cancer (median number, 74 cells per milliliter). We identified the expected EGFR activating
mutation … We detected the T790M mutation, which confers drug resistance, in circulating …

… lung cancers with somatic EGFR mutations and that prospective clinical trials of EGFR inhibition
in patients with EGFR mutations … Identification of EGFR mutations in other malignancies, …

… to gefitinib or erlotinib harbor EGFR mutations, not all cases with such mutations demonstrate
a potent drug response. To address the predictive value of EGFR mutations, we analyzed …

… cell lung cancer and the subsequent discovery of activating EGFR mutations have led to an
… of knowledge in the fields of EGFR biology, targeted therapeutics and lung cancer research. …

… EGFR mutations in patients, our understanding of the biology of these … EGFR mutations is
poor compared to classical mutations. In particular, clinical data focused on these mutations is …

… In China, it is also the most common cancer and leading cause of cancer-related … (EGFR)
mutations. NSCLC harboring EGFR mutations constitutes about 10–20% of all lung cancer …

… In conclusion, screening for EGFR mutation is warranted in women with lung cancer, in …
EGFR mutation is feasible using FNAC/core needle biopsy sample. Statistics of EGFR mutation …

… This study reviewed the prevalence of uncommon EGFR mutations and their sensitivity to
EGFR… L858R mutations, indicating that they may benefit from EGFR-TKIs as a first-line therapy. …

… a patient with EGFR-mutant, gefitinib-responsive, advanced non–small-cell lung cancer who
… The DNA sequence of the EGFR gene in his tumor biopsy specimen at relapse revealed the …