Phase II study of erlotinib in advanced non–small-cell lung cancer after failure of gefitinib

BC Cho, CK Im, MS Park, SK Kim, J Chang… - Journal of clinical …, 2007 - ascopubs.org
gefitinib. In the Iressa Survival Evaluation in Lung Cancer (ISEL) study, however, gefitinib
failed to prolong survival in patients with advanced NSCLC after the failure of at least one prior …

Treatment after the failure of gefitinib in patients with advanced or recurrent non-small cell lung cancer

R Maruyama, H Wataya, T Seto, Y Ichinose - Anticancer research, 2009 - ar.iiarjournals.org
… treatment after the failure of gefitinib. The present study retrospectively evaluated the
clinical value of continuing gefitinib administration after the failure of initial gefitinib treatment. …

Pooled analysis of the reports of erlotinib after failure of gefitinib for non-small cell lung cancer

K Kaira, T Naito, T Takahashi, E Ayabe, R Shimoyama… - Lung Cancer, 2010 - Elsevier
… The use of erlotinib after gefitinib failure in patients with non-small cell lung cancer (NSCLC)
is … clinical reports to better understand the effectiveness of erlotinib after failure of gefitinib. …

Randomized phase II study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy

ST Kim, JE Uhm, J Lee, J Sun, I Sohn, SW Kim… - Lung Cancer, 2012 - Elsevier
Gefitinib and erlotinib are potent EGFR TKIs, with antitumor activity. In this … of gefitinib and
erlotinib was evaluated as the second-line therapy for advanced non-small cell lung cancer (…

Comparison of gefitinib versus erlotinib in patients with nonsmall cell lung cancer who failed previous chemotherapy

ST Kim, J Lee, J Kim, YW Won, JM Sun, J Yun… - Cancer, 2010 - Wiley Online Library
… NSCLC patient population after failure of chemotherapy.13, 14 … Lung Cancer, IDEAL 1 and
2) demonstrated that gefitinib was … Evaluation in Lung Cancer trial comparing gefitinib with …

Erlotinib in advanced non-small-cell lung cancer after gefitinib failure

ZT Zhou, XH Xu, Q Wei, M Lu, J Wang… - Cancer chemotherapy and …, 2009 - Springer
… In our study, The DCR of erlotinib after gefitinib failure was similar to that in Cho’s study.
Most patients who benefit from erlotinib had also benefited from prior gefitinib treatment, but we …

Phase I study of irinotecan and gefitinib in patients with gefitinib treatment failure for non-small cell lung cancer

A Horiike, K Kudo, E Miyauchi, F Ohyanagi… - … journal of cancer, 2011 - nature.com
lung cancer (NSCLC) after failure of gefitinib therapy. Pre-clinical studies have demonstrated
that gefitinib-… can be used as a treatment option for patients failing gefitinib monotherapy. …

The characteristics and failure pattern of gefitinib responders with postoperative recurrence of pulmonary adenocarcinoma

F Shoji, T Yano, I Yoshino, D Mori, F Yamasaki… - European Journal of …, 2008 - Elsevier
… activity against advanced or recurrent non-small cell lung cancer (NSCLC). However, most …
of gefitinib in our limited study (p = 0.036). In 9 of 12 responders, gefitinib treatment failed due …

… patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase …

VA Miller, V Hirsh, J Cadranel, YM Chen, K Park… - The lancet …, 2012 - thelancet.com
lung adenocarcinoma with previous treatment failure on … major cancer conferences using
keywords “NSCLC”, “gefitinib”, “… with non-small-cell lung cancer (NSCLC) after chemotherapy …

Gefitinib in non-small cell lung cancer

K Tamura, M Fukuoka - Expert opinion on pharmacotherapy, 2005 - Taylor & Francis
… in Lung cancer), gefitinib failed to prolong survival compared with placebo in patients with
advanced NSCLC who had failed … which predict to response to gefitinib. Two types of somatic …