Where next for gefitinib in patients with lung cancer?
F Blackhall, M Ranson, N Thatcher - The lancet oncology, 2006 - thelancet.com
… gefitinib treatment in never-smokers and in patients of Asian origin. Here, we review the clinical
experience with gefitinib … remains for clinical development of gefitinib in selected patients. …
experience with gefitinib … remains for clinical development of gefitinib in selected patients. …
Practical management of patients with non–small-cell lung cancer treated with gefitinib
NT Shah, MG Kris, W Pao, LB Tyson… - Journal of Clinical …, 2005 - ascopubs.org
… in persons with lung cancer. Many of the principles of management relevant to gefitinib are
distinct … practical guidelines on the use of gefitinib in patients with non–small-cell lung cancer. …
distinct … practical guidelines on the use of gefitinib in patients with non–small-cell lung cancer. …
Gefitinib as first-line treatment for patients with advanced non-small-cell lung cancer with activating epidermal growth factor receptor mutation: Review of the evidence
C Gridelli, F De Marinis, M Di Maio, D Cortinovis… - Lung Cancer, 2011 - Elsevier
… Conference on Lung Cancer, the First-SIGNAL study, oral gefitinib confirmed an improvement
in progression-free survival compared to first-line chemotherapy in patients with EGFR …
in progression-free survival compared to first-line chemotherapy in patients with EGFR …
Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non–small cell lung cancer: a randomized trial
MG Kris, RB Natale, RS Herbst, TJ Lynch Jr, D Prager… - Jama, 2003 - jamanetwork.com
… a fraction of patients with NSCLC progressing after chemotherapy experience both a
decrease in lung cancer symptoms and radiographic tumor shrinkages with gefitinib.ObjectiveTo …
decrease in lung cancer symptoms and radiographic tumor shrinkages with gefitinib.ObjectiveTo …
Overview of gefitinib in non-small cell lung cancer: an Asian perspective
H Jiang - Japanese journal of clinical oncology, 2009 - academic.oup.com
… This review discusses the use of gefitinib in Asian patients with advanced NSCLC using
the extensive clinical data available and also summarizes data on the discovery of the EGFR …
the extensive clinical data available and also summarizes data on the discovery of the EGFR …
Gefitinib in patients with brain metastases from non–small-cell lung cancer: review of 15 clinical cases
Y Namba, T Kijima, S Yokota, M Niinaka… - Clinical lung cancer, 2004 - Elsevier
… Fifteen of the 79 patients who received gefitinib treatment in our institution had clinically
detectable BM at the time of gefitinib induction. Patient characteristics are shown in Table 1. …
detectable BM at the time of gefitinib induction. Patient characteristics are shown in Table 1. …
Clinical benefit of readministration of gefitinib for initial gefitinib-responders with non-small cell lung cancer
H Yokouchi, K Yamazaki, I Kinoshita, J Konishi… - BMC cancer, 2007 - Springer
… Hospital Organization Hokkaido Cancer Center, Sapporo City … was performed during gefitinib
treatment in any of the patients, … cessation of gefitinib, followed by resumption of gefitinib. …
treatment in any of the patients, … cessation of gefitinib, followed by resumption of gefitinib. …
[HTML][HTML] Gefitinib in patients with brain metastases from non-small-cell lung cancer: a prospective trial
GL Ceresoli, F Cappuzzo, V Gregorc, S Bartolini… - Annals of oncology, 2004 - Elsevier
… activity and safety of gefitinib in NSCLC patients with brain metastases. Patients and methods:
From January 2001 to May 2003, 41 consecutive NSCLC patients with measurable brain …
From January 2001 to May 2003, 41 consecutive NSCLC patients with measurable brain …
First-line gefitinib for patients with advanced non–small-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy
A Inoue, K Kobayashi, K Usui, M Maemondo… - Journal of Clinical …, 2009 - ascopubs.org
… Lung cancer is the leading cause of cancer death worldwide, and approximately 80% of
cases are non–small-cell lung cancer (NSCLC). Many patients with NSCLC have advanced …
cases are non–small-cell lung cancer (NSCLC). Many patients with NSCLC have advanced …
Predictors of the Response to Gefitinib in Refractory Non–Small Cell Lung Cancer
KS Kim, JY Jeong, YC Kim, KJ Na, YH Kim, SJ Ahn… - Clinical cancer …, 2005 - AACR
… that gefitinib has potential for treating lung cancers that are … Therefore, 98 patients were
included in this analysis. The … Eleven patients were labeled as having non–small cell lung cancer …
included in this analysis. The … Eleven patients were labeled as having non–small cell lung cancer …
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