Genotyping and genomic profiling of non–small-cell lung cancer: implications for current and future therapies

T Li, HJ Kung, PC Mack, DR Gandara - Journal of Clinical Oncology, 2013 - ascopubs.org
… is an important step for personalized cancer therapy that holds … and genomic profiling in
personalized medicine in lung cancer … and genomic testing discussed in the following sections. …

[HTML][HTML] Genomic profiling of advanced non–small cell lung cancer in community settings: gaps and opportunities

ME Gutierrez, K Choi, RB Lanman, EJ Licitra… - Clinical lung cancer, 2017 - Elsevier
… first-line therapy, and in the Lung Cancer Mutation Consortium study, insufficient tissue was
… not undergo genomic profiling, 22 (7%) died within 30 days of their lung cancer diagnosis. …

Comprehensive genomic profiles of small cell lung cancer

J George, JS Lim, SJ Jang, Y Cun, L Ozretić, G Kong… - Nature, 2015 - nature.com
… the genomes of 110 small cell lung cancers (SCLC), one of the deadliest human cancers. In
… of TP53 and RB1, sometimes by complex genomic rearrangements. Two tumours with wild-…

High-resolution genomic profiles of human lung cancer

G Tonon, KK Wong, G Maulik… - Proceedings of the …, 2005 - National Acad Sciences
… The remarkable degree of overlap between lung cancer subtypes prompted a comparison
with our recently generated high-resolution genomic profile of another lethal epithelial tumor …

Genomic profiling of small-cell lung cancer: the era of targeted therapies

S Umemura, K Tsuchihara, K Goto - Japanese Journal of Clinical …, 2015 - academic.oup.com
… reports describing comprehensive genomic analyses of small-cell lung cancer have been …
-cell lung cancer and have demonstrated that the genomic landscape of small-cell lung cancer

[HTML][HTML] Comprehensive genomic profiling of combined small cell lung cancer

J Zhang, L Zhang, J Luo, T Ge, P Fan… - … lung cancer research, 2021 - ncbi.nlm.nih.gov
… Combined small cell lung cancer (CSCLC) is an uncommon and heterogeneous subtype
of small cell lung cancer (SCLC). However, there is limited data concerning the different …

[HTML][HTML] Utility of comprehensive genomic profiling in directing treatment and improving patient outcomes in advanced non-small cell lung cancer

S Zhao, Z Zhang, J Zhan, X Zhao, X Chen, L Xiao… - BMC medicine, 2021 - Springer
… clinical trial directed by their profiling results. Its impacts on … genomic profiling were
performed to evaluate the extent of clinical benefits offered by comprehensive genomic profiling

[HTML][HTML] Lung cancer genomic signatures

MT Agulló-Ortuño, F López-Ríos, L Paz-Ares - Journal of Thoracic Oncology, 2010 - Elsevier
… we can often identify function associated with some of the genes in a signature, the
challenge is to put this information into perspective with respect to the entire genomic profile. …

Comprehensive genomic profiling identifies novel genetic predictors of response to anti–PD-(L) 1 therapies in non–small cell lung cancer

W Fang, Y Ma, JC Yin, S Hong, H Zhou, A Wang… - Clinical Cancer …, 2019 - AACR
… We performed comprehensive genomic profiling of 78 non–small cell lung cancer (NSCLC) …
for clinical outcomes, we identified novel genomic features that jointly with TMB refine the …

[HTML][HTML] Genomic profiling in non-small-cell lung cancer in young patients. A systematic review

D Viñal, D Martínez, O Higuera, J De Castro - ESMO open, 2021 - Elsevier
… -pathological features and different genomic alterations makes lung cancer in AYA an interesting
… on genomic profiling in AYA with lung cancer [focusing on non-small-cell lung cancer (…