Epidermal growth factor receptor mutations in lung cancer
SV Sharma, DW Bell, J Settleman, DA Haber - Nature Reviews Cancer, 2007 - nature.com
… that target the epidermal growth factor receptor (EGFR) provide important insights for new
lung cancer therapies, as well as for the broader field of targeted cancer therapies. We review …
lung cancer therapies, as well as for the broader field of targeted cancer therapies. We review …
Epidermal growth factor receptor family in lung cancer and premalignancy
WA Franklin, R Veve, FR Hirsch, BA Helfrich… - Seminars in …, 2002 - Elsevier
… proteins, particularly overexpression of epidermal growth factor receptor (EGFR) family …
EGF and transforming growth factor alpha. Epidermal growth factor receptor overexpression is …
EGF and transforming growth factor alpha. Epidermal growth factor receptor overexpression is …
The biology of epidermal growth factor receptor in lung cancer
GV Scagliotti, G Selvaggi, S Novello, FR Hirsch - Clinical Cancer Research, 2004 - AACR
The prognostic significance of epidermal growth factor receptor (EGFR) expression in lung
cancer and, more importantly, its ability to predict response to anti-EGFR therapies, are …
cancer and, more importantly, its ability to predict response to anti-EGFR therapies, are …
Epidermal growth factor receptors in non-small cell lung cancer
D Veale, T Ashcroft, C Marsh, GJ Gibson… - … journal of cancer, 1987 - nature.com
… Our results suggest thatepidermal growth factor receptor may play a part in the genesis or
spread of lung cancers. This is the third common primary carcinoma in which we have found a …
spread of lung cancers. This is the third common primary carcinoma in which we have found a …
Mutations of the Epidermal Growth Factor Receptor Gene in Lung Cancer: Biological and Clinical Implications
T Kosaka, Y Yatabe, H Endoh, H Kuwano, T Takahashi… - Cancer research, 2004 - AACR
… epidermal growth factor receptor(EGFR) gene occur in a subset of patients with lung cancer
… To gain further insights in the role of EGFR in lung carcinogenesis, we sequenced exons 18…
… To gain further insights in the role of EGFR in lung carcinogenesis, we sequenced exons 18…
[HTML][HTML] Screening for epidermal growth factor receptor mutations in lung cancer
… growth factor receptor (EGFR), PI3K, BRAF, and K-ras genes are generally nonoverlapping
and identifiable in approximately 40% of non–small-cell lung cancers… small-cell lung cancers. …
and identifiable in approximately 40% of non–small-cell lung cancers… small-cell lung cancers. …
[HTML][HTML] Epidermal growth factor receptor (EGFR) in lung cancer: an overview and update
G Bethune, D Bethune, N Ridgway… - Journal of thoracic …, 2010 - ncbi.nlm.nih.gov
… Mutations in epidermal growth factor receptor have been discovered in association with
some lung cancers. Lung adenocarcinomas with mutated epidermal growth …
some lung cancers. Lung adenocarcinomas with mutated epidermal growth …
The Fibroblast Growth Factor Receptor Inhibitor PD173074 Blocks Small Cell Lung Cancer Growth In vitro and In vivo
OE Pardo, J Latigo, RE Jeffery, E Nye, R Poulsom… - Cancer research, 2009 - AACR
… Our previous work showed that fibroblast growth factor-2 induces … growth factor receptor
(FGFR) inhibitor PD173074 blocks H-510 and H-69 SCLC proliferation and clonogenic growth in …
(FGFR) inhibitor PD173074 blocks H-510 and H-69 SCLC proliferation and clonogenic growth in …
[HTML][HTML] Epidermal growth factor receptor inhibition in lung cancer: status 2012
… Lung cancer is the most common cause of cancer deaths. … However, with the understanding
of lung cancer biology, and … patients with non–small-cell lung cancer (NSCLC). Epidermal …
of lung cancer biology, and … patients with non–small-cell lung cancer (NSCLC). Epidermal …
Epidermal growth factor family of receptors in preneoplasia and lung cancer: perspectives for targeted therapies
FR Hirsch, GV Scagliotti, CJ Langer, M Varella-Garcia… - Lung cancer, 2003 - Elsevier
… in patients with lung cancer [4], [5… lung cancer. The gene mechanisms for the protein
expression will be discussed, and for the HER2, differences between lung cancer and breast cancer …
expression will be discussed, and for the HER2, differences between lung cancer and breast cancer …
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