[HTML][HTML] Lung cancer-initiating cells: a novel target for cancer therapy

BJ Morrison, JC Morris, JC Steel - Targeted oncology, 2013 - Springer
… Investigating putative cancer-initiating cells in lung cancer will … 1) lung cancer, (2) stem cells,
and the role of cancer-initiating … characteristics associated with lung cancer-initiating cells; …

Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy

JP Sullivan, JD Minna, JW Shay - Cancer and Metastasis Reviews, 2010 - Springer
… However, despite the relatively rapid pace of cancer stem cell research in … cancers, similar
progress in lung cancer remains hampered in part due to an incomplete understanding of lung

Differential roles of STAT3 in the initiation and growth of lung cancer

J Zhou, Z Qu, S Yan, F Sun, JA Whitsett, SD Shapiro… - Oncogene, 2015 - nature.com
… STAT3 prevents lung cancer initiation by … lung cancer progression by promoting cancer
cell growth. These studies also provide a mechanistic basis for targeting STAT3 to lung cancer

Mesenchymal stem cells enhance lung cancer initiation through activation of IL-6/JAK2/STAT3 pathway

HS Hsu, JH Lin, TW Hsu, K Su, CW Wang, KY Yang… - Lung cancer, 2012 - Elsevier
… cells (MSCs) and IL-6 in lung cancer has not been well-addressed. We aimed to determine
if MSCs can enhance the ability of tumor initiation of lung cancer cells, and link MSCs with …

Microbes in lung cancer initiation, treatment, and outcome: boon or bane?

H Guo, L Zhao, J Zhu, P Chen, H Wang, M Jiang… - Seminars in Cancer …, 2022 - Elsevier
… and contradictory relationship with lung cancer initiation, treatments, and … lung cancers
based on epidemiological evidence, and antibiotics (ATBs) could dramatically impair anti-cancer

The effect of age at smoking initiation on lung cancer risk

KT Hegmann, AM Fraser, RP Keaney, SE Moser… - …, 1993 - journals.lww.com
… to smoke before age 20 had a substantially higher risk of developing lung cancer … of lung
cancer. In this study, up to 52.4% of lung cancer cases in men and up to 73.0% of lung cancer

C-Raf Is Required for the Initiation of Lung Cancer by K-RasG12D

FA Karreth, KK Frese, GM DeNicola, M Baccarini… - Cancer discovery, 2011 - AACR
… in K-Ras–mutant lung cancer. Because genetic ablation is not … G12D –mediated lung cancer
development should stimulate … Given the importance of C-Raf during tumor initiation, such …

The effects of time to treatment initiation for patients with non–small-cell lung cancer in the united states

TR Cushman, B Jones, D Akhavan, CG Rusthoven… - Clinical lung cancer, 2021 - Elsevier
Background The purpose of this study was to determine the effects of time from diagnosis to
treatment (TTI) on survival in patients with nonmetastatic non–small-cell lung cancer (NSCLC…

The effects of NRF2 modulation on the initiation and progression of chemically and genetically induced lung cancer

S Tao, M Rojo de la Vega, E Chapman… - Molecular …, 2018 - Wiley Online Library
… effects of NRF2 on (i) cancer initiation: NRF2 was activated or … Kras G12D or (ii) cancer
progression: NRF2 was modulated … the initiation of environmental factor-induced cancer but has …

[HTML][HTML] Lung cancer tumorigenicity and drug resistance are maintained through ALDHhiCD44hi tumor initiating cells

J Liu, Z Xiao, SKM Wong, VPC Tin, KY Ho, J Wang… - Oncotarget, 2013 - ncbi.nlm.nih.gov
… for lung cancer control [8-11]. However, a deeper understanding of the cell targets and
maintenance mechanisms is essential for further therapy development. Lung cancerlung cancer