Circulating and tumor myeloid-derived suppressor cells in resectable non–small cell lung cancer

Y Yamauchi, S Safi, C Blattner… - American journal of …, 2018 - atsjournals.org
… accumulation and chronic inflammatory factor levels on RFS in patients with lung cancer,
we analyzed their interrelationships using Kaplan-Meier survival curves. Two …

… myeloid-derived suppressor cells and selected cytokines are potentially prognostic of disease progression for patients with non-small cell lung cancer

L Barrera, E Montes-Servín… - Cancer Immunology …, 2018 - Springer
MDSC have been identified in the peripheral blood of NSCLC and small cell lung cancer
patients … to the predominant type of MDSC in cancer patients, with some studies showing that M-…

[HTML][HTML] The prognostic effects of circulating myeloid-derived suppressor cells in non-small cell lung cancer: systematic review and meta-analysis

G Bronte, L Calabrò, F Olivieri, AD Procopio… - Clinical and Experimental …, 2023 - Springer
… The aim of this systematic review is to select studies for a meta-analysis, which compares
prognosis between patients with high vs low circulating MDSC levels. We collected hazard …

[HTML][HTML] Circulating levels of monocytic myeloid-derived suppressor cells (M-MDSC) and CXCL-8 in non-small cell lung cancer (NSCLC)

SS Zadian, IM Adcock, B Salimi, E Mortaz - Tanaffos, 2021 - ncbi.nlm.nih.gov
… According to the findings of this small-scale pilot study, circulating M-MDSCs, but not G-MDSC,
are elevated in NSCLC patients compared to healthy volunteers. There was a trend …

[HTML][HTML] Myeloid-derived suppressor cells—new and exciting players in lung cancer

Z Yang, J Guo, L Weng, W Tang, S Jin… - Journal of hematology & …, 2020 - Springer
… They showed that the lncRNA RUNXOR exhibited upregulated expression in MDSCs isolated
from the peripheral blood of LC patients and that the expression of RUNX1, a target gene …

A circulating subpopulation of monocytic myeloidderived suppressor cells as an independent prognostic/predictive factor in untreated non‐small lung cancer patients

EK Vetsika, F Koinis, M Gioulbasani… - Journal of …, 2014 - Wiley Online Library
… of MDSCs and their association with the clinical outcome were investigated in non-small
cell lung cancer (NSCLC) patients. The percentages and correlation between MDSCs and …

Immunoregulation and Clinical Implications of ANGPT2/TIE2+ M-MDSC Signature in Non–Small Cell Lung Cancer

E Lauret Marie Joseph, C Laheurte, M Jary… - Cancer immunology …, 2020 - AACR
… to immunotherapy for several cancers. Here, we describe … MDSCs (M-MDSC) overexpressing
TIE2, the receptor for angiopoietin-2 (ANGPT2), in patients with non–small cell lung cancer

[HTML][HTML] Enhanced circulating ILC2s and MDSCs may contribute to ensure maintenance of Th2 predominant in patients with lung cancer

Y Wu, Y Yan, Z Su, Q Bie, X Chen… - Molecular …, 2017 - spandidos-publications.com
… or MDSCs in lung cancer remain to be elucidated. In the present study, 36 patients newly
diagnosed with lung cancer based on the guidelines of the International Union Against Cancer

Myeloid suppressor cells and immune modulation in lung cancer

MK Srivastava, Å Andersson, L Zhu… - …, 2012 - Taylor & Francis
… interaction of tumors with MDSCs that lead to dysregulation of … in lung cancer modulate
the activities of MDSCs and impact … In cancer patients, MDSCs are identified by surface …

[HTML][HTML] … -like cells are associated with the primary resistance to immune checkpoint inhibitors in advanced non-small cell lung cancer: an exploratory analysis

G Bronte, E Petracci, S De Matteis, M Canale… - Frontiers in …, 2022 - frontiersin.org
… A high number of MDSCs have been observed in patients with NSCLC, breast cancer,
and head and neck cancer (13). Increased levels of circulating MDSCs have recently been …