… C20 antibody can thus be considered as a reliable antibody with high affinity for p16INK4A
protein and no false positives, whereas p16 INK4A (Pharmingen) immunostaining is more …

… The p16 INK4a (p16) tumor suppressor gene … lung cancer, the leading cause of cancer-related
deaths in the US We have determined the timing of this event in an animal model of lung …

… frequency of P16 INK4a in serum or bronchoalveolar fluid (BAF)/sputum in lung cancer
patients has been widely discussed; however, the exact diagnostic performance of P16 INK4a as …

… Promoter hypermethylation of the p16 INK4a gene … lung cancer, using a modified protocol
of semi-nested methylation-specific-PCR (MSP). The results showed hypermethylated p16 …

… non-small cell lung cancer. Our results indicate that p16 INK4a promoter hypermethylation
predicts a poor 5-year survival rates for patients with resectable non-small cell lung cancer, …

Expression of p16INK4a/p16a and p19ARF/p16b is frequently altered in non-small cell lung
cancer and correlates with p53 overexpr Page 1 Expression of p16INK4a/p16a and p19ARF/…

… p16 INK4A inactivation, correlates with loss of protein expression, and represents a frequent
event in lung cancer. … Moreover, the fact that p16 INK4A methylation has also been found in …

… Most Rb-positive NSCLC lung cancer cells lines expressed no detectable p161N@(4@@…
A similar situation occurred in primary human lung cancers: p16INK4Aprotein was Un …

… The p16 INK4a protein expression was examined in 30 chromate lung cancers, by which we
could measure the p16 … Twenty-five normal lung and bronchial tissues, adjacent to tumors …

… The p16 INK4a protein inhibits cyclin-dependent kinase 4, a key regulator of progression
through the G 1 phase of the cell cycle. Methylation of CpG islands in the promoter region is an …