… by the presence of a mutation. Herein, we … cancer, the molecular basis of p53 mutation in
lung cancer, and the normal molecular and cellular roles of p53 that are abrogated during lung …

… We detected 23 pS3 mutations within these exons in 22 lung cancers; no p53 … To our
knowledge, no mutations of codon 175 of p53 in lung cancers have been reported. The reason for …

… In summary, these analyses show that p53 mutations in lung cancer from smokers
carryhighly significant fingerprints of exposure to tobacco smoke components, in particular BaP. …

… the association between sex and p53 mutations in lung cancer. In the present study, sex
was not an independent predictor of p53 mutations in the multiple logistic regression analysis. …

… their occurrence along the p53 gene. … lung tumors with silent p53 mutations. Accordingly,
we offer here a selection-based explanation of why lung cancers with nonsilent p53 mutations …

… The p53 gene was frequently mutated or inactivated in all types of human lung cancer. The
… In the present work we have identified p53 abnormalities in 17 of 30 (57%) lung cancer cell …

… -associated lung cancer, and genetic mutations are regarded to be more common in patients
with tobacco-associated lung cancer than in never-smokers. Lung cancer from smokers …

… (27) reported that there was no difference in survival times between patients having lung
cancer with positive p53 protein immunostaining and those having lung cancer with negative im…

… of p53 mutations found in lung cancer … mutations in lung cancers are G to T transversions,
whereas G to A transitions are more common in other tumors such as breast and colon cancers …

… The presence of a p53 alteration was not related to … p53 alterations and the presence of a
K‐ras mutation. This was reflected in the overall postoperative survival data: patients with p53 …