Tuberous-sclerosis complex-related cell signaling in the pathogenesis of lung cancer

A Fuchs, K König, LC Heukamp, J Fassunke, J Kirfel… - Diagnostic …, 2014 - Springer
… EGFR associated signaling pathways in lung cancer. Phosphorylation, ie activation of the …
and may play a putative pathogenic role in lung cancer pathogenesis. Arrows represent …

[HTML][HTML] TBX2 subfamily suppression in lung cancer pathogenesis: a high-potential marker for early detection

AA Khalil, S Sivakumar, FA San Lucas, T McDowell… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… subfamily expression in normal bronchi was associated with lung cancer status (P < 10 −5 )
in … NSCLC pathogenesis and may serve as a high-potential biomarker for early lung cancer

[HTML][HTML] Analysis on the pathogenesis and treatment progress of NRG1 fusion-positive non-small cell lung cancer

H Li, L Xu, H Cao, T Wang, S Yang, Y Tong… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
… , thereby contributing to the complex etiopathogenesis of lung cancer (33). Although the
precise mechanisms underlying the pathogenesis of NRG1 fusion-positive NSCLC remain …

The regulation of CPNE1 ubiquitination by the NEDD4L is involved in the pathogenesis of non-small cell lung cancer

R Zhang, W Zhang, Y Zeng, Y Li, J Zhou, Y Zhang… - Cell Death …, 2021 - nature.com
pathogenesis of tumor disease. The use of small molecule tyrosine kinase inhibitors and
immunotherapy can increase the survival benefit in lung cancer … development of lung cancer, …

[HTML][HTML] Interstitial Lung Diseases and Non-Small Cell Lung Cancer: Particularities in Pathogenesis and Expression of Driver Mutations

F Sampsonas, P Bosgana, V Bravou, A Tzouvelekis… - Genes, 2024 - mdpi.com
… molecular and pathogenetic pathways that can interconnect Interstitial Lung Diseases and
lung cancer, … Results: Common pathogenetic pathways have been identified in sites of chronic …

Epidermal growth factor receptor abnormalities in lung cancer. Pathogenetic and clinical implications

L Prudkin, II Wistuba - Annals of diagnostic pathology, 2006 - Elsevier
… of a subset of lung cancers with relatively … lung cancer have supported the notion that
different molecular mechanisms and pathways are involved in the pathogenesis of lung cancer

Rate of pathogenic germline variants in patients with lung cancer

S Sorscher, J LoPiccolo, B Heald, E Chen… - JCO Precision …, 2023 - ascopubs.org
cancer. However, GGT is not yet recommended for all patients diagnosed with lung cancer
(LC… that supports a significant frequency of identifying pathogenic germline variants (PGVs) in …

Roles of Wnt/β-catenin signaling pathway regulatory long non-coding RNAs in the pathogenesis of non-small cell lung cancer

S Lin, Y Zhen, Y Guan, H Yi - Cancer management and research, 2020 - Taylor & Francis
… by small cell lung cancer. Citation1 Despite the prolific research on lung cancer, its pathogenesis
has remained insufficiently known and the merely 15% 5-y survival rate of lung cancer

The mevalonate pathway and innate immune hyper-responsiveness in the pathogenesis of COPD and lung cancer: potential for chemoprevention

RP Young, RJ Hopkins - Current Molecular Pharmacology, 2017 - ingentaconnect.com
… Given the central role of innate immunity in the pathogenesis of COPD [15-18], we suggest
that targeting the mevalonate pathway makes pharmacological sense. This pathway has also …

Frequent allelic imbalance suggests involvement of a tumor suppressor gene at 1p36 in the pathogenesis of human lung cancers

S Nomoto, N Haruki, Y Tatematsu… - … and Cancer, 2000 - Wiley Online Library
… We used seven polymorphic markers in addition to TP73 to examine 61 primary lung
cancers. … of the molecular pathogenesis of lung cancer. Genes Chromosomes Cancer 28:342–346, …