The role of EGFR inhibitors in nonsmall cell lung cancer
… growth factor receptor-targeting drugs in the treatment of nonsmall cell lung cancer. … factor
receptor inhibitors of tyrosine kinase enzymatic activity that prevent epidermal growth factor …
receptor inhibitors of tyrosine kinase enzymatic activity that prevent epidermal growth factor …
[HTML][HTML] Role of epidermal growth factor receptor in lung cancer and targeted therapies
TC Liu, X Jin, Y Wang, K Wang - American Journal of Cancer …, 2017 - ncbi.nlm.nih.gov
… as lung cancer therapy. The current review focuses on the role of EGFR in lung cancer …
Particularly, these EGFR inhibitors were successful in suppressing lung cancer progression …
Particularly, these EGFR inhibitors were successful in suppressing lung cancer progression …
Receptor tyrosine kinases and inhibitors in lung cancer
E Pisick, S Jagadeesh, R Salgia - The Scientific World Journal, 2004 - Wiley Online Library
… therapies for lung cancers. This review will discuss the RTKs that are involved in lung cancers
and … We will specifically discuss receptors such as epidermal growth factor receptor, c-Kit …
and … We will specifically discuss receptors such as epidermal growth factor receptor, c-Kit …
… of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer
T Mitsudomi, Y Yatabe - Cancer science, 2007 - Wiley Online Library
… treatment of lung cancer is beginning to open, and through these efforts, it will be possible
to slow the progression of lung cancer and eventually, to decrease mortality from lung cancer. (…
to slow the progression of lung cancer and eventually, to decrease mortality from lung cancer. (…
Synergistic antitumor activity of sorafenib in combination with epidermal growth factor receptor inhibitors in colorectal and lung cancer cells
E Martinelli, T Troiani, F Morgillo, G Rodolico… - Clinical Cancer …, 2010 - AACR
… cancer cells. Lung cancer cells had the highest levels of vascular endothelial growth
factors (VEGF) A, B, and C, and of VEGF receptors as compared with colorectal cancer cells. …
factors (VEGF) A, B, and C, and of VEGF receptors as compared with colorectal cancer cells. …
[HTML][HTML] Second-generation epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer
GJ Riely - Journal of Thoracic Oncology, 2008 - Elsevier
… Of the nearly 200,000 people diagnosed with lung cancer each year in the United States, …
cell lung cancer (NSCLC) with somatic mutations in the epidermal growth factor receptor gene (…
cell lung cancer (NSCLC) with somatic mutations in the epidermal growth factor receptor gene (…
The next generation of epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of lung cancer
… in patients with EGFRm lung cancer who develop disease … tumors respond to the selective
inhibition of third-generation EGFR … In summary, EGFR inhibition in patients with NSCLC has …
inhibition of third-generation EGFR … In summary, EGFR inhibition in patients with NSCLC has …
Dominant-negative Notch3 receptor inhibits mitogen-activated protein kinase pathway and the growth of human lung cancers
N Haruki, KS Kawaguchi, S Eichenberger, PP Massion… - Cancer research, 2005 - AACR
… lung cancer cell lines, suggesting that Notch3 activation is a common event in lung cancer
(… in resected, human lung tumors, we probed lung cancer tissue microarrays with an antibody …
(… in resected, human lung tumors, we probed lung cancer tissue microarrays with an antibody …
Nonsmall Cell Lung Cancer Therapy: Insight into Multitargeted Small‐Molecule Growth Factor Receptor Inhibitors
… circumvent inhibition … lung cancer cells carry out for growth, proliferation, angiogenesis,
and metastasis by using GFRs, and how they are being cotargeted by small-molecule inhibitors …
and metastasis by using GFRs, and how they are being cotargeted by small-molecule inhibitors …
The selective tyrosine kinase inhibitor STI571 inhibits small cell lung cancer growth
GW Krystal, S Honsawek, J Litz, E Buchdunger - Clinical Cancer Research, 2000 - AACR
… At least 70% of small cell lung cancers express the Kit receptor tyrosine kinase and its
ligand, stem cell factor (SCF). Numerous lines of evidence have demonstrated that this …
ligand, stem cell factor (SCF). Numerous lines of evidence have demonstrated that this …