… its incorporation into subsequent targeted therapy trials in lung cancer with other actionable
… profiling of lung cancers has also revealed the genetic heterogeneity in lung cancers, where …

… Targeted therapy has emerged as an … cell lung cancer (NSCLC). Herein, we review and
analyze recent literature, discuss the targeting pathways and ongoing clinical trials in lung cancer…

… This review focuses on the targeted therapies in lung cancer: the molecular biomarkers that
… from these targeted therapies, the basic molecular biology principles behind these therapies, …

… management of non-small cell lung cancer (NSCLC). NSCLC … a known driver mutation,
targeted therapy is pushing the … well as the development of targeted agents available to treat …

… of individualized therapy. In this article we review clinical data for molecular-targeted therapies
in … Nonetheless, for most patients with NSCLC targeted therapies have not dramatically …

… This Review outlines the current state-of-the-art research for targeted therapy in NSCLC. …
discusses other targeted therapies that are being developed to treat patients with this cancer. …

… targeting EGFR family members, novel EML4-ALK inhibitors and MEK inhibitors are currently
in clinical development. Availability of targeted therapies … in use of targeted therapy, with a …

… , targeted therapy continues to provide durable responses. Advances in molecular and
immunohistochemical techniques have made it possible to usher lung cancer … targeted therapy, …

… cancer growth. In this comprehensive review, we look back at developments in targeted therapy
for advanced non-small-cell lung cancer, … cases less so, to target EGFR, VEGF and ALK. …

… improved chemotherapy, targeted therapies and better supportive care. New insights into
the pathogenesis of lung cancer are helping to identify more targets for novel therapies. Some …