… Transforming growth factor (TGF)-β isoforms play a pivotal role in the … of TGF-β1 and
TGF-β3 on the main processes controlling ECM deposition using primary human lung fibroblasts. …

… In this study, we chose primary lung fibroblasts as a model system to … by TGF-. We
demonstrate that JunD is a key mediator of TGF-induced effects in primary human lung fibroblasts. …

… Fibroblast activation of TGF-β by the αvβ8 integrin leads to CCL2- and CCL20-dependent
dendritic cell migration promoting airway remodeling (66), and ASM cells can activate …

… However, our data show that in lung fibroblast cultures, TGF-/3 does not stimulatenuclear
labeling at 48 h, including cultures that received a second dose after 24 h of incubation (Fig. 7). …

… fibroblasts. Since many of the studies on the effects of TGF beta on pulmonary fibroblasts …
of TGF beta on HGF, FGF7, and FGF10 expression in the presence and absence of serum. …

… -α induced TGF-β 1 expression in lung fibroblasts … lung fibroblasts, post- transcriptional
events initiated by TNF-α appear to be a major contributor for the increased expression of TGF-β …

… This perpetuates the aberrant wound healing process by inducing extracellular matrix
production, promoting myofibroblast recruitment and activation from resident lung fibroblast, …

… that lung fibroblasts represent a major target of pirfenidone in IPF treatment. Moreover, in this
study we show for the first time that pirfenidone inhibited TGF-β-… behavior in IPF fibroblasts. …

… This study demonstrates that TGF-β1 induces α-SMA expression and collagen
production in human lung fibroblasts via ERK1/2 activation, GSK-3β inhibition and nuclear β-catenin …

… of adult human lung fibroblasts (HLF… lungs of patients with and without pulmonary fibrosis.
We determined the effects of two proinflammatory cytokines, transforming growth factor-p (TGF-…