Noninvasive imaging of experimental lung fibrosis

Y Zhou, H Chen, N Ambalavanan, G Liu… - American Journal of …, 2015 - atsjournals.org
… review various noninvasive imaging methods that are currently used for evaluation of
lung fibrosis in small animal models. These include micro-CT, MRI, nuclear imaging (specifically …

[HTML][HTML] Non-invasive imaging of idiopathic pulmonary fibrosis using cathepsin protease probes

NP Withana, X Ma, HM McGuire, M Verdoes… - Scientific reports, 2016 - nature.com
… can be used for non-invasive imaging of cancer margins … lung fibrosis, tissues from
human clinical samples and first-in-human imaging studies to demonstrate the value of non-invasive

[HTML][HTML] Recent advances in the non-invasive assessment of fibrosis using biomarkers

AL Tatler - Current Opinion in Pharmacology, 2019 - Elsevier
… or for the potential staging of fibrosis severity this study highlights that cell-free DNA
methylation profiles merit further investigation as biomarkers of lung fibrosis. Imaging biomarkers …

Fibrosis imaging: current concepts and future directions

M Baues, A Dasgupta, J Ehling, J Prakash… - Advanced drug delivery …, 2017 - Elsevier
non-invasive imaging techniques for monitoring fibrosis in systemic autoimmune diseases,
in parenchymal organs (such as liver, kidney, lung … assessment in lung fibrosis, serum levels …

… resonance imaging for noninvasive assessment of lung fibrosis onset and progression: Cross-validation and comparison of different magnetic resonance imaging …

GV Velde, E De Langhe, J Poelmans… - Investigative …, 2014 - journals.lww.com
lung MRI contrast and acquisition methods to visualize disease onset and progression in the
bleomycin-induced mouse model of lung fibrosis … and histological measures of lung fibrosis. …

A multimodal imaging approach based on micro-CT and fluorescence molecular tomography for longitudinal assessment of bleomycin-induced lung fibrosis in mice

F Ruscitti, F Ravanetti, G Donofrio, Y Ridwan… - JoVE (Journal of …, 2018 - jove.com
lung fibrosis are invasive terminal procedures. The goal of this work is to monitor lung
fibrosis through noninvasive imaging … approach for real time non-invasive monitoring of IPF …

Noninvasive monitoring of pulmonary fibrosis by targeting matrix metalloproteinases (MMPs)

Y Cai, L Zhu, F Zhang, G Niu, S Lee… - Molecular …, 2013 - ACS Publications
lung fibrosis model for diagnosis and monitoring PF treatment response. By optical imaging
of … With the development of molecular imaging techniques, noninvasive imaging has been …

Targeting Activated Fibroblasts for non-invasive detection of Lung Fibrosis

C Ferreira, Z Rosenkrans, K Bernau, M Moore, F Valla… - 2021 - Soc Nuclear Med
lung diseases, such as idiopathic pulmonary fibrosis (IPF), are characterized by progressive
lung fibrosis … A major challenge in IPF clinical management is lack of a direct noninvasive

[HTML][HTML] Longitudinal micro-computed tomography-derived biomarkers quantify non-resolving lung fibrosis in a silicosis mouse model

K Dekoster, T Decaesteker, N Berghen… - Scientific Reports, 2020 - nature.com
… it to be a model more relevant to human disease; (2) we assess the added value of
longitudinal imaging using µCT to provide non-invasive biomarkers characterizing pulmonary …

Noninvasive imaging of tumor progression, metastasis, and fibrosis using a nanobody targeting the extracellular matrix

N Jailkhani, JR Ingram, M Rashidian… - Proceedings of the …, 2019 - National Acad Sciences
… in whole lungs and regions of lung fibrosis) … lungs and lung fibrosis region than for
sham-treated controls. We conclude that 64 Cu-NJB2 detects early pulmonary fibrosis noninvasively