… In an effort to better define the association between antiplatelet therapy and lung injury, a
sensitivity analysis was performed evaluating the relationship between antiplatelet therapy and …

Aim: Platelet function is intricately linked to the pathophysiology of critical Illness, and some
studies have shown that antiplatelet therapy (APT) may decrease mortality and incidence of …

… [70], indicating that the inhibition of cPLA2-initiated pathways may provide a therapeutic
approach to acute lung injury. On the contrary, cPLA2 could act with the reactive oxygen species …

… Antiplatelet therapy can attenuate lung injury by impeding platelet activation and surface
adhesion protein expression, such as glycoprotein IIb/IIIa receptor, P-selectin, and intracellular …

… Over the past decade, only low-tidal volume ventilation has been shown to improve
outcomes from ventilator-associated lung injury and lung dysfunction. However, severely …

… ; US Critical Illness and Injury Trials Group; Lung Injury Prevention Study Investigators.
Association of prehospitalization aspirin therapy and acute lung injury: results of a multicenter …

… At sites of lung injury, platelets activation act as signalling molecules to propagate an …
within the alveolar space, prolonging the period of lung injury and hypoxia [46]. An experimental …

… In multivariable analysis controlling for the LIPS and the propensity score for receiving
antiplatelet therapy, the hazard of developing ALI was attenuated with prehospital antiplatelet …

… of antiplatelet therapy in the setting of viral pneumonia. The following 3 issues should be
taken into account when interpreting the effect of antiplatelet therapy … and reducing lung injury. …

… Over the last decade, the use of antiplatelet therapy has increased considerably, as a result
… pre-injury anti-platelet therapy was reported to reduce the incidence of acute lung injury in a …