Biotrauma and ventilator-induced lung injury: clinical implications

GF Curley, JG Laffey, H Zhang, AS Slutsky - Chest, 2016 - Elsevier
clinical implications of VILI. Although the term used throughout this review is VILI, the
mechanisms of injury are related to changes in lung … term might be ventilation-induced lung injury. …

Mechanisms and clinical consequences of acute lung injury

V Fanelli, VM Ranieri - Annals of the American Thoracic Society, 2015 - atsjournals.org
… Second, the term acute lung injury was abandoned. Third, … clinicians recognize patients
with the syndrome) was formalized as the following: ARDS is a type of acute diffuse lung injury

Ventilator-induced lung injury: historical perspectives and clinical implications

N De Prost, JD Ricard, G Saumon, D Dreyfuss - Annals of intensive care, 2011 - Springer
… Effect of previous toxic lung injury. Extravascular lung water (Qwl) after mechanical
ventilation in normal rats (open circles) and in rats with mild lung injury produced by α-…

Acute lung injury: a clinical and molecular review

Y Butt, A Kurdowska, TC Allen - Archives of Pathology …, 2016 - meridian.allenpress.com
… Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are a continuum
of lung changes arising from a wide variety of lung injuries, frequently resulting in significant …

Clinical review: the implications of experimental and clinical studies of recruitment maneuvers in acute lung injury

E Piacentini, A Villagrá, J López-Aguilar, L Blanch - Critical care, 2003 - Springer
Mechanical ventilation can cause and perpetuate lung injury if alveolar overdistension, cyclic
collapse, and reopening of alveolar units occur. The use of low tidal volume and limited …

Ventilator-induced lung injury and implications for clinical management

C Edibam - Critical Care and Resuscitation, 2000 - Elsevier
… between clinically apparent ‘barotrauma’ and the more subtle changes in lung structure and
… that as the underlying lung injury worsens, the degree of injury from mechanical ventilation …

Functional pathophysiology of SARS-CoV-2-induced acute lung injury and clinical implications

NM Habashi, L Camporota… - Journal of applied …, 2021 - journals.physiology.org
The worldwide pandemic caused by the SARS-CoV-2 virus has resulted in over 84,407,000
cases, with over 1,800,000 deaths when this paper was submitted, with comorbidities such …

Pressure‐volume relationships in acute lung injury: methodological and clinical implications

S Nunes, A Uusaro, J Takala - Acta anaesthesiologica …, 2004 - Wiley Online Library
… Acute lung injury (ALI) is characterized by impairment of gas exchange and respiratory …
may worsen lung injury due to overdistension and repeated opening and closing of lung units …

Ventilator-induced lung injury, cytokines, PEEP, and mortality: implications for practice and for clinical trials

AS Slutsky, Y Imai - Intensive care medicine, 2003 - Springer
… on the clinical implications of this study. This study demonstrated that PEEP minimizes lung
injury, … These data are in accord with a large body of experimental and clinical evidence …

Clinical epidemiology of acute lung injury

MJ Neff, GD Rubenfeld - Seminars in respiratory and critical …, 2001 - thieme-connect.com
… the term acute lung injury (ALI) was used to describe a broad spectrum of lung dysfunction
… However, we will adopt the AECC terminology and refer to the entire spectrum of lung injury