Matrix regulation of lung injury, inflammation, and repair: the role of innate immunity

PW Noble, D Jiang - Proceedings of the American Thoracic Society, 2006 - atsjournals.org
… between ECM and innate immune receptors in regulating noninfectious lung injury and
repair. … To investigate the role of HA in lung injury and repair, we examined the inflammatory …

Pulmonary innate immune response determines the outcome of inflammation during pneumonia and sepsis-associated acute lung injury

V Kumar - Frontiers in immunology, 2020 - frontiersin.org
innate immune response determines infection severity. For example, the potent innate immune
response generation in the lungs … the pulmonary innate immune response responsible for …

Innate immunity in the lungs

TR Martin, CW Frevert - Proceedings of the American Thoracic …, 2005 - atsjournals.org
… in patients at risk for ventilator-induced lung injury. Because bacterial products, such as
LPS… -induced lung injury by carefully reducing the responsiveness of lung innate immune

The proinflammatory role of HECTD2 in innate immunity and experimental lung injury

TA Coon, AC McKelvey, T Lear… - Science translational …, 2015 - science.org
… Our goal in this study was to investigate the role of HECTD2 in innate immunity and
models of experimental lung injury. Several in vitro approaches were used to determine the …

After the storm: regeneration, repair, and reestablishment of homeostasis between the alveolar epithelium and innate immune system following viral lung injury

JD Planer, EE Morrisey - Annual Review of Pathology …, 2023 - annualreviews.org
lunglung's alveolar epithelium following acute lung injury, with an emphasis on the
response to viral infection. Reviews on the pathogenesis of acute lung injury and the host immune

Dietary plasma proteins attenuate the innate immunity response in a mouse model of acute lung injury

M Maijó, L Miró, J Polo, J Campbell… - British Journal of …, 2012 - cambridge.org
… in a mouse model of acute lung inflammation, based on the intranasal administration of
LPS. Specifically, we studied the innate immune system because this mediates the defence …

Ace2 and innate immunity in the regulation of SARS-CoV-2-induced acute lung injury: A review

L Qu, C Chen, T Yin, Q Fang, Z Hong, R Zhou… - International journal of …, 2021 - mdpi.com
… enzyme (ACE) expressed in human lungs and immune cells. ACE2 is known to antagonize
the … by innate immune cells. This review discusses the role of ACE2 and innate immunity in …

Innate immune recognition in infectious and noninfectious diseases of the lung

B Opitz, V van Laak, J Eitel, N Suttorp - American journal of …, 2010 - atsjournals.org
… in mouse models of acute lung injury and chronic lung diseases, it is an intriguing
possibility that these approaches might also show therapeutic benefits in human patients with …

Advances in lung ischemia/reperfusion injury: unraveling the role of innate immunity

Q Li, H Nie - Inflammation Research, 2024 - Springer
… Various immune components of the innate immune system play critical roles in lung injury
after ischemia/reperfusion. Preventing cell death and the release of DAMPs, interrupting …

Innate immunity of the lung: from basic mechanisms to translational medicine

D Hartl, R Tirouvanziam, J Laval, CM Greene… - … of innate immunity, 2018 - karger.com
… elastase, and myeloperoxidase can cause direct or indirect cell toxicity and subsequent
lung injury [57–59], as well as airway obstruction via an increase in mucus viscosity [60–62]. …