… been observed during spontaneous breathing with airway … use of APRV with spontaneous
breathing as a primary … randomly assigned to either breathe spontaneously with APRV (APRV …

… by spontaneous breathing with airway pressure release ventilation (APRV) in acute lung
injury. … The authors hypothesized that spontaneous breathing results in better aeration of lung …

… by strong spontaneous breathing effort can worsen lung injury. When spontaneous breathing
is … pressure and tidal volume should be strictly controlled to prevent further lung injury. …

… ; no one has yet evaluated the effects of spontaneous breathing in severe lung injury. We
investigated the effects of spontaneous breathing in two different severities of lung injury …

… , and breathing effort. Furthermore, it is unknown whether the severity of lung injury (ARDS …
,8 –10 we describe the spontaneous breathing pattern and WOB of patients with ARDS/ALI. …

… lung injury, our findings cannot be extrapolated to other models or clinical conditions where
lung recruitability is limited and/or lung injury … levels of SB on lung injury and inflammation. …

… injured lungs under mechanical ventilation (MV), but mechanisms are still poorly understood
6,7 . Spontaneously breathing … the effects of spontaneous breathing (SB) on lung injury and …

… Spontaneous breathing (SB) might decrease alveolar collapse in the most dependent lung
zones, leading to less ventilator-induced lung injury (VILI) ( 8–… stress/strain of lung tissue, and …

… Putensen C, Rasanen J, Lopez FA: Ventilation–perfusion distributions during mechanical
ventilation with superimposed spontaneous breathing in canine lung injury. Am J Respir Crit …

… Patient self-inflicted lung injury (P-SILI) … how to better protect lungs during spontaneous
breathing, one important question is whether spontaneous breathing can induce lung injury. Our …