The impact of successive infections on the lung microenvironment

A Didierlaurent, J Goulding, T Hussell - Immunology, 2007 - Wiley Online Library
… As the mucosa is a major portal of entry and replication site for many pathogens, studying
the interaction between microbes and the host mucosa is crucial to our understanding of …

Host–microbe cross-talk in the lung microenvironment: implications for understanding and treating chronic lung disease

R Gosens, PS Hiemstra, IM Adcock… - … Respiratory Journal, 2020 - Eur Respiratory Soc
pulmonary fibrosis (IPF) [13] and, recently, lung cancer [14] have been associated with a
microbial dysbiosis in the lung… in the bacterial composition drive disease pathogenesis or if they …

[PDF][PDF] Characteristics of pathogenic microbes in lung microenvironment of lung cancer patients without respiratory infection

M Zhang, Y Zhang, Y Han, X Zhao, Y Sun - J BUON, 2021 - jbuon.com
… cancer (LC) patients without any respiratory infection. In this work, we … of pathogenic microbes
in lung microenvironment of non-small cell lung cancer (NSCLC) patients using pathogen

Lung epithelial cells interact with immune cells and bacteria to shape the microenvironment in tuberculosis

AM de Waal, PS Hiemstra, THM Ottenhoff, SA Joosten… - Thorax, 2022 - thorax.bmj.com
… the lung microenvironment more closely. Herein, we discuss the interplay between lung EC,
… epithelium, which represents a major part of the pathogensmicroenvironment. Moreover, …

Host–microorganism interactions in lung diseases

BJ Marsland, ES Gollwitzer - Nature Reviews Immunology, 2014 - nature.com
… the microbial constituents of healthy and diseased lungs, … the airway microenvironment is
shifting respiratory research … a habitat suitable for pathogenic bacteria, resulting in dysbiosis of …

[HTML][HTML] Host and pathogen communication in the respiratory tract: Mechanisms and models of a complex signaling microenvironment

SB Berry, AJ Haack, AB Theberge, S Brighenti… - Frontiers in …, 2020 - frontiersin.org
… diseases are a leading cause of morbidity and mortality across the globe, encompassing
a diverse range of conditions from infections with pathogenic microorganisms to underlying …

[HTML][HTML] Lung microbiome: new insights into the pathogenesis of respiratory diseases

R Li, J Li, X Zhou - Signal transduction and targeted therapy, 2024 - nature.com
… Studying microbial communities will further clarify the pathogenesis and development of …
They vary according to position because each location creates a distinct microenvironment. The …

[HTML][HTML] The lung microbiota: role in maintaining pulmonary immune homeostasis and its implications in cancer development and therapy

M Sommariva, V Le Noci, F Bianchi, S Camelliti… - Cellular and Molecular …, 2020 - Springer
… Indeed, several studies indicate that lung bacterial … reprogram the antitumor immune
microenvironment. In the present … and pathogens raises the question about the ability of lung

[HTML][HTML] Role of lung and gut microbiota on lung cancer pathogenesis

Y Zhao, Y Liu, S Li, Z Peng, X Liu, J Chen… - Journal of Cancer …, 2021 - Springer
… These studies show that lung bacterial represents a major component of the lung tumor
microenvironment and the gut–lung axis allows indirect modification of lung bacterial

[HTML][HTML] The dynamic lung microbiome in health and disease

JG Natalini, S Singh, LN Segal - Nature Reviews Microbiology, 2023 - nature.com
… of the lung microbiome is quite distinct from other microbial … activation in the lung
microenvironment can be disrupted by the … respiratory pathogens, such as Staphylococcus and …