… Although they are less prevalent than in the paracortex because they are replaced by
follicular dendritic cells during lymph node development, conduits are an important pathway for …

… However, in spite of the large number of models proposed for drug development … of the
lymph node (LN) has not been provided yet [13,19]. Only recently has the need for developing an …

… characteristics developed to … lymphatic vessels and the lymph nodes to which they drain.
This review describes the current state of interstitial-, lymphatic-, and lymph node-targeted drug …

… A well-designed lymphatic-targeted system … , development of nanotechnologies and
emerging biomaterials have gained increasing attention in developing lymph-node-targeted drug-…

… , LNs present some of the same types of problem for drug delivery as the brain. Possessed of
no … We show here the development of a two-stage approach inspired by the way particulate …

… development. Based on the hypothesis that lymphocytes isolated from regional draining
lymph nodes … Therefore, AgSKl can be considered a candidate for drug development and our …

… Despite the fact that most of the developed in vitro lymph node models have not been … do
hold a huge potential to revolutionize drug discovery and drug development. In particular, the …

… increase nanoparticle delivery to lymph nodes: (1) direct lymph node injection, (… lymph
nodes, and multiple studies have demonstrated its capability in enhancing immunostimulant drugs…

… as carriers are widely developed to achieve efficient lymph node targeting and improve
vaccine-… of lymph node targeting vaccine delivery based on the anatomy of lymph nodes and …

… that have been developed to enable lymph node delivery are discussed. … lymphatic drug
delivery systems [21], we describe in this review the lymphatic physiology relevant to lymph node…