[HTML][HTML] … T lymphocyte chimerism after allogeneic hematopoietic transplantation is predictive for relapse of acute myeloid leukemia and myelodysplastic syndromes

HC Lee, RM Saliba, G Rondon, J Chen… - Biology of Blood and …, 2015 - Elsevier
lymphocyte chimerism [24]. We sought to examine the effect of mixed T lymphocyte chimerism
… the potential utility of T lymphocyte chimerism analysis between post-transplantation day +…

Myelodysplastic syndrome

G Mufti, AF List, SD Gore, AYL Ho - ASH Education Program …, 2003 - ashpublications.org
… In summary, the recommendations are that chimerism … marrow; that lineage-specific chimerism
should be the assay of … human thoracic duct lymphocytes suppresses T lymphocytes. It …

Leukemia lineage-specific chimerism analysis is a sensitive predictor of relapse in patients with acute myeloid leukemia and myelodysplastic syndrome after …

J Mattsson, M Uzunel, L Tammik, J Aschan, O Ringden - Leukemia, 2001 - nature.com
lymphocyte infusion (DLI) than those with hematological evidence of disease. In those with
acute leukemia and myelodysplastic syndromes (… Therefore, chimerism analysis, using PCR …

[HTML][HTML] … limitations of donor T cell chimerism after myeloablative allogeneic stem cell transplantation for acute myeloid leukemia and myelodysplastic syndromes

E Wong, K Mason, J Collins, B Hockridge… - Biology of Blood and …, 2017 - Elsevier
… for acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Therapeutic options
for … , either alone or in combination with donor lymphocyte infusions; or a second alloSCT. …

[HTML][HTML] … lymphocyte infusion after T cell–depleted allogeneic hematopoietic stem cell transplantation for acute myelogenous leukemia and myelodysplastic syndromes

P Krishnamurthy, VT Potter, LD Barber… - Biology of Blood and …, 2013 - Elsevier
… patients with progressively declining donor CD3 chimerism or relapsed disease post-TCD …
requirement for pDLI by repeat chimerism assessment. The chimerism response to pDLI was …

Myelodysplastic syndrome

WK Hofmann, HP Koeffler - Annu. Rev. Med., 2005 - annualreviews.org
Lymphocytes are probably not involved in the clonal hematopoiesis in MDS (24), but … in a
chimerism to encourage a graft-versus-MDS/AML effect. This approach is still investigational. …

CD34+ lineage specific donor cell chimerism for the diagnosis and treatment of impending relapse of AML or myelodysplastic syndrome after allo-SCT

F Rosenow, A Berkemeier, U Krug… - Bone marrow …, 2013 - nature.com
CD34+ lineage specific donor cell chimerism for the diagnosis and treatment of impending
relapse of AML or myelodysplastic syndrome after allo-SCT | Bone Marrow Transplantation …

Myelodysplastic syndromes

AF List, J Vardiman, JPJ Issa… - ASH Education Program …, 2004 - ashpublications.org
… 9 and acute lymphocytic leukemia (ALL), 10 and it is likely to play a similar role in MDS. …
facilitate donor engraftment and establish complete donor chimerism. Kröger et al 21 reported …

Characterization of lineage‐specific chimaerism in patients with acute leukaemia and myelodysplastic syndrome after allogeneic stem cell transplantation before and …

P Bader, K Stoll, S Huber, A Geiselhart… - British journal of …, 2000 - Wiley Online Library
… cell subpopulations when routine serial analysis of chimerism had revealed increasing MC
in the … Interestingly, freshly obtained donor lymphocytes showed alloreactivity towards these …

Donor cell myelodysplastic syndrome after allogeneic stem cell transplantation responding to donor lymphocyte infusion: case report and literature review

R Komrokji, JJ Ifthikharuddin, RE Felgar… - American journal of …, 2004 - Wiley Online Library
… ment for patients with myelodysplastic syndrome (MDS)… chimerism analysis at relapse
showed hematopoiesis to be entirely of donor origin confirming donor cell MDS. Donor lymphocyte