Effect of selectively knocking down key metabolic genes in Müller glia on photoreceptor health

W Shen, SR Lee, AE Mathai, R Zhang, J Du, MX Yam… - Glia, 2021 - Wiley Online Library
… between Müller glia and photoreceptors indicates that Müller glia may provide important
metabolites to support photoreceptors (… Müller glial microvilli form a dense network to ensheath …

[HTML][HTML] CD44 signaling in Müller cells impacts photoreceptor function and survival in healthy and diseased retinas

M Ayten, T Straub, L Kaplan, SM Hauck… - Journal of …, 2024 - Springer
… inflammation, characterized by Müller cell activation and … in Müller cells from our Pde6b
STOP/STOP RP mouse model. To gain a more detailed understanding of CD44’s role in healthy

Müller cells in the healthy and diseased retina

A Bringmann, T Pannicke, J Grosche, M Francke… - Progress in retinal and …, 2006 - Elsevier
… It has been known for many years that retinal neurons (particularly, photoreceptor cells) are
highly susceptible to various forms of injury including insufficient blood supply. By contrast, …

[HTML][HTML] Neural and Müller glial adaptation of the retina to photoreceptor degeneration

HO Leinonen, E Bull, Z Fu - Neural Regeneration Research, 2023 - journals.lww.com
… Collectively, Müller glia may support photoreceptor health by providing the necessary … ,
or that Müller glia may undergo neurogenesis to replace degenerated photoreceptors. Further …

Müller glial cells in retinal disease

A Bringmann, P Wiedemann - Ophthalmologica, 2011 - karger.com
Müller cells support the survival of photoreceptors and neurons, are responsible for the … to
the photoreceptors [9] and buffer mechanical deformations of the retinal tissue [10]. Müller cells

[图书][B] Müller cells in the healthy and diseased retina

A Reichenbach, A Bringmann - 2010 - books.google.com
… The ONL contains the somata of the photoreceptor cells, rods (R) and cones (C). Generally,
the nuclei of the cones are larger than those of the rods, and lie at the outermost border of …

A journey into the retina: Müller glia commanding survival and death

PV Subirada, MC Paz, ME Ridano… - European Journal of …, 2018 - Wiley Online Library
cells in other neuronal tissues, it is certain that retinal health … in nonvascular cells of the
retina: neurons (photoreceptors, … cells), microglia (resident phagocytes) and macroglia (Müller

[HTML][HTML] Müller glia phagocytose dead photoreceptor cells in a mouse model of retinal degenerative disease

S Sakami, Y Imanishi, K Palczewski - The FASEB Journal, 2019 - ncbi.nlm.nih.gov
… of Müller glia in the phagocytosis of rod photoreceptor cells. During the early stage of retinal
degeneration, Müller glial cellsMüller glia could also contribute to phagocytosis in healthy

Adult human Müller glia cells are a highly efficient source of rod photoreceptors

SG Giannelli, GC Demontis, G Pertile, P Rama… - … cells, 2011 - academic.oup.com
Müller glia from adult human retinas and propagated them in vitro revealing for the first time
their ability to differentiate into rod photoreceptors. … a rod photoreceptor commitment with a …

Retinal macroglial responses in health and disease

R de Hoz, B Rojas, AI Ramírez… - BioMed research …, 2016 - Wiley Online Library
cells of the retina are the astrocytes and the Müller cells. … Müller cells react to retinal injury
by establishing a glial scar that fills … , replacing degenerated neurons and photoreceptors [124]. …