[HTML][HTML] The functional roles, cross-talk and clinical implications of m6A modification and circRNA in hepatocellular carcinoma

S Qin, Y Mao, X Chen, J Xiao, Y Qin… - International Journal of …, 2021 - ncbi.nlm.nih.gov
… interplay mechanisms between m6A modification and circRNA in HCC carcinogenesis and
development. And we demonstrated the clinical implications of m6A modifiers and circRNAs …

The roles and implications of RNA m6A modification in cancer

X Deng, Y Qing, D Horne, H Huang… - Nature Reviews Clinical …, 2023 - nature.com
N 6 -Methyladenosine (m 6 A), the most prevalent internal modification in eukaryotic mRNA,
has been extensively and increasingly studied over the past decade. Dysregulation of RNA …

[HTML][HTML] The interplay between m6A modification and non-coding RNA in cancer stemness modulation: mechanisms, signaling pathways, and clinical implications

S Qin, Y Mao, H Wang, Y Duan… - International Journal of …, 2021 - ncbi.nlm.nih.gov
m6A modification in cancer stemness modulation are rarely investigated. In this review, we
elucidate the recent findings on the relationships of m6A modification, … m6A modification and …

[PDF][PDF] RNA m6A modification in cancers: molecular mechanisms and potential clinical applications

C Gu, X Shi, C Dai, F Shen, G Rocco, J Chen, Z Huang… - The innovation, 2020 - cell.com
clinical therapeutic targets for cancers. In this review, we emphasize on the underlying
mechanisms of m6A modifications in tumorigenesis and further introduce the potential m6A

[HTML][HTML] N6-methyladenosine (m6A) in cancer therapeutic resistance: Potential mechanisms and clinical implications

D Wang, Y Zhang, Q Li, A Zhang, J Xu, Y Li, W Li… - Biomedicine & …, 2023 - Elsevier
… of m6A modification modulators and potential therapeutic strategies have profound implications
for the clinical … mechanisms of m6A modification in CTR and the recent progress of m6A

Biological roles of the RNA m6A modification and its implications in cancer

J Hong, K Xu, JH Lee - Experimental & Molecular Medicine, 2022 - nature.com
… (m 6 A) modification of RNA transcripts is the most prevalent and abundant internal modification
in … Extensive studies have indicated that dysregulated m 6 A modification and m 6 A-…

The role of m6A modification in physiology and disease

C Yang, Y Hu, B Zhou, Y Bao, Z Li, C Gong… - Cell death & …, 2020 - nature.com
… WTAP is a subunit of the methyltransferase, which promotes the recruitment of the m6A
bind to m 6 A-modified RNA through conserved m6A-binding domains and play different …

Characterization of Modification Patterns, Biological Function, Clinical Implication, and Immune Microenvironment Association of m6A Regulators in Pancreatic …

K Fang, H Qu, J Wang, D Tang, C Yan, J Ma… - Frontiers in …, 2021 - frontiersin.org
modification may modulate various biological processes. Nonetheless, clinical implications
of m 6 A modification … A modification patterns in pancreatic cancer based on m 6 A regulators. …

Roles and therapeutic implications of m6A modification in cancer immunotherapy

J Pan, T Huang, Z Deng, C Zou - Frontiers in immunology, 2023 - frontiersin.org
… Furthermore, m6A modification was not only found in tumors but also in ischemic diseases
(… We also highlight the potential clinical applications and future directions of m6A modification

[PDF][PDF] m6A modification in coding and non-coding RNAs: roles and therapeutic implications in cancer

H Huang, H Weng, J Chen - Cancer cell, 2020 - cell.com
… of 3–5 m6A modifications in each mRNA, and many m6A sites are … The deposition of m6A
modification in the transcriptome is … , the clinical implications of the global m6A abundance may …