Integrated proteomic and transcriptomic landscape of macrophages in mouse tissues

J Qie, Y Liu, Y Wang, F Zhang, Z Qin, S Tian… - Nature …, 2022 - nature.com
proteomic and transcriptomic data of 12 macrophage populations Integrated analysis of our
proteomic … the macrophage proteome data, we constructed a TF interaction network of the 12 …

Integrated proteomics and genomics strategies bring new insight into Candida albicans response upon macrophage interaction

E Fernández-Arenas, V Cabezón, C Bermejo… - … & Cellular Proteomics, 2007 - ASBMB
… albicans-macrophage interaction. We provide evidence of a rapid … proteomics, and network
analyses is a powerful strategy to better understand the complex host-pathogen interactions

Context-enriched interactome powered by proteomics helps the identification of novel regulators of macrophage activation

A Halu, JG Wang, H Iwata, A Mojcher, AL Abib… - Elife, 2018 - elifesciences.org
Integrating the novel network topology with transcriptomics and proteomics revealed top …
Many different proteins interact with each other to control inflammation; gaining an insight …

Integrated analysis of genomics and proteomics reveals that CKIP-1 is a novel macrophage migration regulator

L Zhang, X Xia, M Zhang, Y Wang, G Xing, X Yin… - Biochemical and …, 2013 - Elsevier
… As macrophage is a key cell type in innate immunity, we then used murine macrophage
RAW264.7 cells to discover CKIP-1 interacting … -1 is a novel regulator of macrophage migration. …

Global proteomics insights for a novel small compound targeting the non-integrin Laminin Receptor in a macrophage cell model

A Haffner, M Figueiredo Neto, CS Umbaugh… - Frontiers in Drug …, 2023 - frontiersin.org
… To analyze the protein-protein interactions involved in the downregulated proteome, we
utilized Cytoscape as a visualization tool to explore similarities and differences across the …

Data‐Independent Acquisition‐Based Quantitative Proteomics Analysis Reveals Dynamic Network Profiles during the Macrophage Inflammatory Response

L Li, L Chen, X Lu, C Huang, H Luo, J Jin, Z Mei… - …, 2020 - Wiley Online Library
… by forming a tight interaction network. Data … macrophage inflammatory responses to LPS.
Additionally, this work presents a transcriptome-integrated proteomics analysis of macrophage

Comprehensive proteomics analysis reveals metabolic reprogramming of tumor-associated macrophages stimulated by the tumor microenvironment

D Liu, C Chang, N Lu, X Wang, Q Lu… - Journal of Proteome …, 2017 - ACS Publications
… Stimulated macrophage, TAMs, in turn play an important role in the maintenance of the
tumor microenvironment through secreting anti-inflammatory cytokines or by interaction with …

Defining the proteomic landscape of cultured macrophages and their polarization continuum

TCL Oates, PL Moura, S Cross… - … and Cell Biology, 2023 - Wiley Online Library
… protein–protein interaction networks to facilitate … the integrative proteomic analyses performed
in our study not only establishes this study as an unparalleled investigation of macrophage

Integrated functional analysis of the nuclear proteome of classically and alternatively activated macrophages

JE Wiktorowicz, IH Chowdhury, S Stafford… - Mediators of …, 2019 - Wiley Online Library
proteomic study (Figures 6 and 8(a)) and provide us confidence in the accuracy and reliability
of our integrated proteomic … of Jun N-terminal kinase arrested its interaction with c-Jun and …

Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2

H Specht, E Emmott, AA Petelski, RG Huffman… - Genome biology, 2021 - Springer
… , suggesting that macrophage heterogeneity may emerge in … regulatory interactions, such
as interactions between the … in bulk proteomic experiments to integrate quantitative proteomic