… And this further defects the ROS production and leads to M2 macrophage polarization [122].
In type I diabetes NOD murine model, the deficiency of NADPH oxidase-derived superoxide …

Mitochondria are signaling hubs in cellular physiology that play a role in inflammatory
diseases. We found that partial inhibition of the mitochondrial ATP synthase in the intestine of …

… M2 macrophages have key differences in ROS production … the role of ROS on macrophage
polarization and function. The … M2 macrophages versus anti-tumorigenic M1 macrophages …

… In the current comprehensive review, we dissect the role of ROS in macrophage polarization,
and analyze how ROS production links metabolism and inflammation in diabetes and its …

… The attenuation in the respiratory chain will also allow M1 macrophages to produce ROS,
as will the NADPH produced by the pentose phosphate pathway, which is required for the …

… -regulate ROS production in this experiment. To confirm the function of ROS in M2 macrophage
polarization, we … We found the production of ROS increased significantly along with M2 …

… M2-like macrophage polarization is of particular pathophysiological consequence in the …
polarization. Future studies to better understand the role of ROS production in macrophage …

… Our study uncovered a novel mechanism by which mitochondrial dysfunction via ROS
production promotes macrophage polarization toward the M1 phenotype by impairing autophagic …

… ROS production mediated by these receptors. Our results demonstrate that the polarization
state of macrophages… determines the cell’s capacity for phagocytosis and production of ROS. …

… Thus, while M2-polarized macrophages have an increased dependence on the TCA cycle
… -polarized macrophages have increased dependence on the TCA cycle for ROS production …