Enhanced M1/M2 macrophage ratio promotes orthodontic root resorption

D He, X Kou, Q Luo, R Yang, D Liu… - Journal of Dental …, 2015 - journals.sagepub.com
resorption, but the underlying mechanism remains unclear. In this study, we examined the
mechanism by which the ratio of M1 to M2 macrophage polarization affects root resorption

Cellular and molecular pathways leading to external root resorption

A Iglesias-Linares… - Journal of dental …, 2017 - journals.sagepub.com
… M2-like macrophages associated with root resorption and root surface repair processes …
root resorption (increased M1:M2 ratio). The mechanism explaining this is that M1 macrophages

CXCL12/CXCR4 mediates orthodontic root resorption via regulating the M1/M2 ratio

XY Fang, YX Zhan, XM Zhou, LN Wu… - Journal of Dental …, 2022 - journals.sagepub.com
… /M2 macrophage ratio in the PDL and promotes root resorption. Upon application of mechanical
force, the PDL resident macrophage … M1 macrophages promote osteoclastic activity and …

Root resorption and immune system factors in the Japanese

M Nishioka, H Ioi, S Nakata… - The Angle …, 2006 - meridian.allenpress.com
… group (P = .030 and .001), with a mean odds ratio of 2.794 … the root resorption group (P =
.063), with a mean odds ratio of … from the monocyte/macrophage lineage.17 Odontoclasts are …

Pathogenesis of non‐infection related inflammatory root resorption in permanent teeth: A narrative review

S Lin, AM Marvidou, R Novak… - International …, 2023 - Wiley Online Library
… During this phase macrophages and clastic cells act to eliminate the damaged tissue and
bone, eventually enabling root resorption and bone repair as part of wound healing. …

Periodontal Fibroblasts—Macrophage Crosstalk in External Inflammatory Root Resorption

HRS Rajeshwari, A Kishen - Journal of Endodontics, 2023 - Elsevier
… /macrophage (Mφ) lineage on exposure to key growth factors such as macrophage colony-…
Increased M1 to M2 ratios are shown to be associated with root resorption. M1 Mφ promote …

A mouse model of inflammatory root resorption induced by pulpal infection

K Balto, R White, R Mueller, P Stashenko - Oral Surgery, Oral Medicine …, 2002 - Elsevier
… The high contrast of dentin to thymol-filled root canals with a linear attenuation ratio of …
in this model therefore primarily reflects inflammatory cytokine expression by macrophages

Pathophysiological mechanisms of root resorption after dental trauma: a systematic scoping review

KM Galler, EM Grätz, M Widbiller, W Buchalla… - BMC Oral Health, 2021 - Springer
… , where an increased ratio of OPG to RANKL constitutes another mechanism to prevent the
… into macrophages. Attracted by chemotactic signals, monocytes and macrophages take up …

Expression of inflammatory cytokines and chemokines in replanted permanent teeth with external root resorption

JV Bastos, TA Silva, EA Colosimo, MIS Côrtes… - Journal of …, 2017 - Elsevier
… inflammatory external root resorption (IERR) and replacement external root resorption (RERR) …
in extracted human teeth presenting with external root resorption (ERR) after replantation. …

Proinflammatory mediators related to orthodontically induced periapical root resorption in rat mandibular molars

Y Matsumoto, S Sringkarnboriboon… - European Journal of …, 2017 - academic.oup.com
macrophages around blood vessels, and endothelial cells in the inflammatory area. COX-2
and PGE 2 were detected in the root resorption lacunae mainly in monocytes, macrophages, …