… Our results demonstrate that defects in DNA maintenance methylation in the embryo, not
in the mother, are associated with abnormal embryonic implantation and development. The …

… DNA methylation pattern maintenance during … abnormal brain development and cause
fetal alcohol spectrum disorders (FASD), with symptoms ranging from craniofacial abnormalities …

… DNA methylation, explore the known enzymatic activities responsible for both establishment
and maintenance of DNA methylation … arise during early embryonic development in humans, …

… marked in sperm so that it could attract DNA methylation during embryonic development. …
increase the risk of epigenetic abnormalities and give rise to imprinted-related diseases. …

… embryonic development, cells are directed toward their future lineages, and DNA methylation
… two distinct modes of DNA methylation activity: maintenance methylation and de novo …

… importance for mammalian embryonic development. … of DNA methylation and its establishment,
maintenance and … to undergo DNA methylation relies on a combination of the unusual …

… pluripotency stages of embryonic development. Nevertheless… of DNA methylation in the
establishment and maintenance of … known to bear epigenetic abnormalities and to retain somatic …

… Following the first DNA replication cycle in the absence of maintenance DNA … methylation
changes at specific gene loci have been associated with aberrant fetal growth and abnormal …

… level of genomic methylation, but they selectively cause abnormal methylation at several …
patterns of CpG islands during germ-cell and early embryonic development. Another possibility …

… De novo and maintenance DNA methylation … development, highly methylated primordial
germ cells migrate to the genital ridge and then undergo loss and reacquisition of methylation. …