Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study

F Cappuzzo, T Ciuleanu, L Stelmakh, S Cicenas… - The lancet …, 2010 - thelancet.com
Maintenance therapy with erlotinib for patients with NSCLC is well tolerated and significantly
prolongs PFS compared with placebo. First-line maintenance with erlotinib could be …

[HTML][HTML] Gefitinib or erlotinib as maintenance therapy in patients with advanced stage non-small cell lung cancer: a systematic review

X Chen, Y Liu, OD Røe, Y Qian, R Guo, L Zhu, Y Yin… - PloS one, 2013 - journals.plos.org
… This study investigated maintenance gemcitabine or erlotinib versus observation, following
induction chemotherapy. Only the data of erlotinib and observation arms were extracted for …

[HTML][HTML] Survival benefit with erlotinib maintenance therapy in patients with advanced non-small-cell lung cancer (NSCLC) according to response to first-line …

B Coudert, T Ciuleanu, K Park, YL Wu, G Giaccone… - Annals of oncology, 2012 - Elsevier
… similar and significant benefits with maintenance erlotinib, compared with placebo, for both
the SD and CR/PR groups (Figure 1A and 1B). The HR for erlotinib benefit was 0.68 in the …

[HTML][HTML] Maintenance erlotinib versus erlotinib at disease progression in patients with advanced non-small-cell lung cancer who have not progressed following …

S Cicènas, SL Geater, P Petrov, Y Hotko, G Hooper… - Lung Cancer, 2016 - Elsevier
… were randomized to receive blinded maintenance erlotinib 150 mg/day (‘early erlotinib’) or
… open-label erlotinib (‘late erlotinib’); patients who progressed on erlotinib received approved …

Approval summary: erlotinib maintenance therapy of advanced/metastatic non-small cell lung cancer (NSCLC)

MH Cohen, JR Johnson, S Chattopadhyay… - The …, 2010 - academic.oup.com
… For drugs such as erlotinib and … of maintenance therapy is being evaluated [11–13]. The
present manuscript concerns the FDA's recent approval of erlotinib as first-line maintenance

Role of erlotinib in first-line and maintenance treatment of advanced non-small-cell lung cancer

N Reguart, AF Cardona, R Rosell - Cancer management and …, 2010 - Taylor & Francis
… and the good toxicity profile of erlotinib make it a … of erlotinib therapy in advanced NSCLC.
It summarizes current data and perspectives of erlotinib in upfront treatment and maintenance

The SATURN trial: the value of maintenance erlotinib in patients with non-small-cell lung cancer

JW Neal - Future Oncology, 2010 - Future Medicine
… Based on this study, the EMA and FDA both approved erlotinib in 2010 as a maintenance
for the effect of maintenance treatment is that the ‘switch maintenance’ treatment may simply …

Erlotinib: as maintenance monotherapy in non-small-cell lung cancer

VJ Muir, S Dhillon - BioDrugs, 2011 - Springer
… use as maintenance treatment in … erlotinib as monotherapy for maintenance treatment in
patients with NSCLC. Medical literature on the use of erlotinib as monotherapy for maintenance

Erlotinib as maintenance therapy in patients with advanced non-small cell lung cancer: a pooled analysis of three randomized trials

F Petrelli, K Borgonovo, M Cabiddu, S Barni - Anti-cancer drugs, 2011 - journals.lww.com
… confirm the benefit of maintenance erlotinib in patients with advanced NSCLC who had not
progressed after four cycles of induction (platinum-based) chemotherapy. Erlotinib leads to a …

[HTML][HTML] Erlotinib in routine clinical practice for first-line maintenance therapy in patients with advanced non-small cell lung cancer (NSCLC)

M Faehling, J Achenbach, P Staib, U Steffen… - Journal of Cancer …, 2018 - Springer
… demonstrated that maintenance therapy with erlotinib after the … (OS) of non-small cell lung
cancer (NSCLC) patients with … III trial comparing erlotinib maintenance to erlotinib second-…