… This paper presents a deterministic model for monitoring the impact of drug resistance on
the transmission dynamics of malaria in a human population. The model has a disease-free …

… model for malaria treatment and spread of drug resistance in an … the transmission rate from
a treated human to the transmission … Our results show that the spread of drug resistance with …

… the evolution of drug resistance - the replacement rate. Comparing this replacement rate to
transmission properties, we show that controlling the emergence of drug resistance within a …

… of transmission does not directly affect the rate at which evolution of antimalarial drug resistance
proceeds. … (‘effectors’) do directly affect the dynamics of resistance as illustrated below. …

… transmission intensity. The influence of transmission intensity on the evolution of drug resistance
… is known however on how epidemiological dynamics at the population level modulates …

… Key assumptions are that the phenotypic cost of drug resistance is a lower intrinsic growth
rate in the absence of drug, and that the drug-induced reduction can be approximated from …

… mathematical model to describe malaria transmission and the spread of drug resistance.
The model is strongly … Modeling transmission dynamics and the spread of anti-malarial drug …

… The main factors affecting the evolution of drug resistance in malaria according to theoretical
… of spread of drug resistance is the proportion of infected hosts that are treated with drugs. A …

… with drug resistant compared with drug sensitive malaria parasites. It is the ratio of transmission
potential in drug resistant versus sensitive infections that drives the spread of resistance. …

… Impact of Heterogeneous Biting on Transmission and Multiplicity of Infection. Heterogeneous
biting has a significant impact on the transmission dynamics of malaria (A). Because the …