Malaria vaccine trials in a wormy world

M Nacher - Trends in parasitology, 2001 - cell.com
… effect in vaccinated individuals without helminth infections. This should be of great concern
in vaccine trials, considering the importance of malaria. Many adverse effects of vaccines are …

Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2

O Nouatin, JB Mengue, JC Dejon-Agobé… - PLoS neglected …, 2021 - journals.plos.org
… The present analysis assessed the effect of helminths on GMZ2, a malaria vaccine … not
infected with helminths and protected against CHMI, indicating efficacy of the candidate vaccine in …

Co‐infection of helminths and malaria: modulation of the immune responses to malaria

FC Hartgers, M Yazdanbakhsh - Parasite immunology, 2006 - Wiley Online Library
… of co-infection that will affect the interaction, such as type and intensity of helminth infection
and … out the possible importance of helminth infections for the evaluation of malaria vaccines. …

Malaria vaccine efficacy: overcoming the helminth hurdle

JV Cruz-Chan, M Rosado-Vallado… - … Review of Vaccines, 2010 - Taylor & Francis
… on the effect of helminth infection in mice on the immunogenicity and protective efficacy of
two distinct malaria vaccine candidates, a transmission-blocking DNA vaccine based on Pfs25 …

Reduced protective efficacy of a blood-stage malaria vaccine by concurrent nematode infection

Z Su, M Segura, MM Stevenson - Infection and immunity, 2006 - Am Soc Microbiol
helminth parasites exacerbate primary malarial infection (27, … of a helminth infection in areas
where malaria is endemic may … of vaccine-induced protective immunity against malaria (26). …

[HTML][HTML] Impact of malaria and helminth infections on immunogenicity of the human papillomavirus-16/18 AS04-adjuvanted vaccine in Tanzania

J Brown, K Baisley, B Kavishe, J Changalucha… - Vaccine, 2014 - Elsevier
… at the Month 7 visit, one month after the scheduled vaccine dose 3… association of malaria
parasitaemia and helminth infection with … vaccine dose in African females aged 10–25 years. …

Malaria and helminth interactions in humans: an epidemiological viewpoint

TW Mwangi, JM Bethony, S Brooker - Annals of Tropical Medicine …, 2006 - Taylor & Francis
… that helminth infections may alter susceptibility to clinical malaria, … the consequences of
co-infection, with studies yielding … of helminth infections on malaria, and of malaria on helminth

Epidemiology of helminth infections and their relationship to clinical malaria in southwest Uganda

AE Shapiro, EM Tukahebwa, J Kasten… - Transactions of the …, 2005 - academic.oup.com
… a significant association between helminth infection and malaria, along with existing … infection
is more complex than hypothesized models of helminth-associated susceptibility to malaria

[HTML][HTML] Epidemiological study of the association between malaria and helminth infections in Nigeria

AM Efunshile, T Olawale, CR Stensvold… - The American journal …, 2015 - ncbi.nlm.nih.gov
… the prevalence of helminths in control children … malaria and helminth infection, we stratified
our analysis by age. In children < 5 and 6–10 years old, the prevalence of helminth infection

Vaccination against helminth parasite infections

JP Hewitson, RM Maizels - Expert review of vaccines, 2014 - Taylor & Francis
Vaccine development for helminth infections has progressed through several scientific
generations from live, attenuated organisms (using irradiation Citation[20]), biochemical fractions …