Genetic diversity and protective efficacy of the RTS, S/AS01 malaria vaccine
DE Neafsey, M Juraska, T Bedford… - … England Journal of …, 2015 - Mass Medical Soc
… The RTS,S/AS01 vaccine targets the … has partial protective efficacy against clinical and
severe malaria disease in infants and children. We investigated whether the vaccine efficacy was …
severe malaria disease in infants and children. We investigated whether the vaccine efficacy was …
Correlates of malaria vaccine efficacy
DI Stanisic, MBB McCall - Expert Review of Vaccines, 2021 - Taylor & Francis
… efficacy against controlled human malaria infections (CHMI) and against naturally acquired
infections. Expert Opinion: Effective vaccination … disappointing efficacy of malaria vaccine …
infections. Expert Opinion: Effective vaccination … disappointing efficacy of malaria vaccine …
Malaria prevention: from immunological concepts to effective vaccines and protective antibodies
IA Cockburn, RA Seder - Nature immunology, 2018 - nature.com
… that must be overcome to improve malaria-vaccine efficacy with current approaches. This …
review of all malaria-vaccine trials or to encompass the field of transmission-blocking vaccines (…
review of all malaria-vaccine trials or to encompass the field of transmission-blocking vaccines (…
Reduced protective efficacy of a blood-stage malaria vaccine by concurrent nematode infection
Z Su, M Segura, MM Stevenson - Infection and immunity, 2006 - Am Soc Microbiol
… efficacy of malaria vaccines in humans. We established a murine coinfection model involving
blood-stage Plasmodium chabaudi AS malaria … the protective efficacy of a malaria vaccine. …
blood-stage Plasmodium chabaudi AS malaria … the protective efficacy of a malaria vaccine. …
The RTS, S malaria vaccine
S Casares, TD Brumeanu, TL Richie - Vaccine, 2010 - Elsevier
… protection afforded by RTS,S and to build a more efficacious second generation vaccine
against malaria… This review will focus on current knowledge about the protective efficacy of RTS,…
against malaria… This review will focus on current knowledge about the protective efficacy of RTS,…
Vaccine efficacy: winning a battle (not war) against malaria
P Van de Perre, JP Dedet - The Lancet, 2004 - thelancet.com
… Not only is the burden of malaria, mainly in HIV-infected pregnant women, increasing, but …
might need a malaria vaccine might also be an obstacle to vaccine effectiveness, because of …
might need a malaria vaccine might also be an obstacle to vaccine effectiveness, because of …
Evaluation of SPf66 malaria vaccine efficacy in Brazil
M Urdaneta, A Prata, CJ Struchiner, CE Tosta, P Tauil… - 1998 - arca.fiocruz.br
… is to be a public health tool, we cannot base our conclusions on its efficacy against the
first episode, but on its overall efficacy. Overall protective efficacies of SPf66 malaria vaccine …
first episode, but on its overall efficacy. Overall protective efficacies of SPf66 malaria vaccine …
Pre-erythrocytic malaria vaccines: towards greater efficacy
AVS Hill - Nature Reviews Immunology, 2006 - nature.com
… current malaria vaccine reaches the levels of durable efficacy likely to be required for vaccine
… -liver-stage vaccines in combination produces much greater efficacy and this combination …
… -liver-stage vaccines in combination produces much greater efficacy and this combination …
Long-term efficacy and immune responses following immunization with the RTS, S malaria vaccine
JA Stoute, KE Kester, U Krzych… - The Journal of …, 1998 - academic.oup.com
… The RTS,S malaria vaccine formulations we studied were designed to induce strong
immune responses to the P. falciparum CS antigen. Our data indicate that antibody and cellular …
immune responses to the P. falciparum CS antigen. Our data indicate that antibody and cellular …
Correlating efficacy and immunogenicity in malaria vaccine trials
MBB McCall, PG Kremsner, B Mordmüller - Seminars in Immunology, 2018 - Elsevier
… protection in malaria vaccine development: Does immunogenicity predict malaria vaccine
efficacy … Have immunological correlates accelerated malaria vaccine development in the past …
efficacy … Have immunological correlates accelerated malaria vaccine development in the past …
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