… The highest protective efficacy was observed in volunteers who received the vaccine with
an … yet achieved good evidence of protective efficacy against clinical malaria. Many of these …

… RTS,S/AS02 is a recombinant protein malaria vaccine that … It has been shown to induce
significant protection to challenge … Gambian adults, vaccine efficacy against natural infection …

… malaria vaccine in Africa against CHMI. Plasmodium falciparum SPZ Vaccine was well
tolerated and safe but less immunogenic and protective in Tanzanian men than in US volunteers. …

… The RTS,S malaria vaccine formulations we studied were designed to induce strong
immune responses to the P. falciparum CS antigen. Our data indicate that antibody and cellular …

… communication) — several fold better protection than the 10% protective efficacy against
Pf7G8 at 24 weeks in the present study. Recent evidence has suggested that the RTS,S/AS01 …

… protection against a challenge with P. vivax blood stages. Our results suggest that Pv200L
is a new malaria vaccine … To assess the protective efficacy in Aotus monkeys, we compared …

… second dose, the vaccine was safe and immunogenic." I We report a phase III trial carried
out to determine the protective efficacy of SPf66 against clinical episodes of malaria due to P …

… to optimize malaria vaccines in regard to magnitude and durability of protective efficacy and
the … Thus, we are hopeful that anti-malaria vaccines will soon be important tools in the battle …

… Vaccines using a single allele may have lower efficacy … the efficacy of the CSP-based RTS,S
malaria vaccine may be … falciparum CSP alleles that diverge from the 3D7 vaccine allele, …

… Our approach to malaria vaccine development differs from that of most others in that we are
… ) sporozoite vaccine, and essentially all other approaches to malaria vaccine development …