… The protective efficacy of the combination as compared with the vaccine alone against these
outcomes was 59.6% (95% CI, 54.7 to 64.0), 70.6% (95% CI, 42.3 to 85.0), and 75.3% (95% …

… Because a major goal of malaria vaccine development is to produce vaccines that protect
against sporozoite challenge, we believe that our findings are of critical importance. Much will …

… of efficacy was short, RTS,S is the first pre-erythrocytic vaccine to show clear protection … has
been accelerated by the Malaria Vaccine Initiative, which is funding an efficacy trial of RTS,S …

… malaria vaccine candidates such as RTS,S. Since adjuvants also have a profound effect on
the speed of avidity maturation [11], the effect of avidity on vaccine efficacy … protective efficacy …

… Ongoing clinical trials suggest the efficacy of the se36 vaccine could be increased by …
vaccine formulation. In this study, we assessed the safety, immunogenicity and protective efficacy …

… reducing the global malaria burden (1). … malaria vaccines with >75% efficacy against
clinical malaria and suitable for use in all malaria-endemic areas by 2030 (duration of protection …

… efficacious malaria vaccine that would improve prospects for … protective efficacy against
clinical malaria in Kenyan children (30). Comparison of the degree of homology with the vaccine …

… Protection of humans against malaria by immunization with radiation-attenuated Plasmodium
… Efficacy of RTS,S/ASO2A malaria vaccine against Plasmodium falciparum infection in semi-…

… that prioritizes malaria vaccine … vaccines might improve upon the protective efficacy of RTS,S
or R21 for children, or address the wider malaria scourge by preventing pregnancy malaria, …

… To enhance the efficacy of DNA malaria vaccines, we evaluated the effect on protection of
immunizing with various combinations of DNA, recombinant vaccinia virus, and a synthetic …