[HTML][HTML] Immunogenicity of the RTS, S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised …

MT White, R Verity, JT Griffin, KP Asante… - The Lancet infectious …, 2015 - thelancet.com
… The RTS,S malaria vaccine provides significant efficacy against episodes of clinical malaria
… can be used as a correlate of protection to predict vaccine efficacy over time. The estimated …

The GMZ2 malaria vaccine: from concept to efficacy in humans

M Theisen, B Adu, B Mordmüller… - … review of vaccines, 2017 - Taylor & Francis
… and MSP3 was found to be associated with protection against malaria episodes [Citation46].
In this study, protection against clinical malaria was associated with high levels of IgG …

[HTML][HTML] Enhancing protective immunity to malaria with a highly immunogenic virus-like particle vaccine

KA Collins, R Snaith, MG Cottingham, SC Gilbert… - Scientific reports, 2017 - nature.com
… RTS,S was the first malaria vaccine to … protective efficacy against clinical malaria of 46%
in 5–17 month old children, and 27% in 6–12 week old infants 17 . This protective efficacy

Malaria vaccine development: persistent challenges

AM Vaughan, SHI Kappe - Current opinion in immunology, 2012 - Elsevier
malaria parasites could induce sterile immunity to infection but progress towards efficacious
vaccines for malaria … immune correlates of vaccine-induced sterile protection and essential …

Comparative efficacy of pre-erythrocytic whole organism vaccine strategies against the malaria parasite

J Friesen, K Matuschewski - Vaccine, 2011 - Elsevier
… compared the protective efficacy of different live malaria vaccines. ► … malaria whole-organism
vaccine in mice. ► Late liver-stage arrest of malaria parasites leads to superior protection. …

Progress toward a malaria vaccine: efficient induction of protective anti-malaria immunity

M Tsuji, EG Rodrigues, RS Nussenzweig - 2001 - degruyter.com
… DNA immunization followed by boosting with modified vaccinia virus Ankara: Enhanced
CD8+ T cell immunogenicity and protective efficacy in the influenza and malaria models. …

A review of human vaccine research and development: malaria

MP Girard, ZH Reed, M Friede, MP Kieny - Vaccine, 2007 - Elsevier
… to believe that an efficacious malaria vaccine may have to … In addition, the development of
a malaria vaccine is met with … that the market for a malaria vaccine is viewed as commercially …

Duration of protection with RTS, S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of …

PL Alonso, J Sacarlal, JJ Aponte, A Leach, E Macete… - The Lancet, 2005 - thelancet.com
… /AS02A candidate malaria vaccine confers partial protection for … in children living in a rural
malaria endemic area of African. … protective efficacy of this vaccine against clinical malaria are …

Efficacy of murine malaria sporozoite vaccines: implications for human vaccine development

JE Egan, JL Weber, WR Ballou, MR Hollingdale… - Science, 1987 - science.org
… potential vaccies against malaria, the protective efficacy of sporozoite subunit vaccines was
Protective efficacy of these vaccines was determined by intravenous challenge with 500 to …

Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara

J Schneider, SC Gilbert, TJ Blanchard, T Hanke… - Nature medicine, 1998 - nature.com
… in protective efficacy against malaria sporozoite challenge. The complete protection observed
in … /6 mice is particularly encouraging as no vaccination protocol designed to induce strong …