… of establishing the initial efficacy of malaria vaccines and drugs. This challenge model has
been most useful in predicting the efficacy in the field of pre-erythrocytic vaccines, in particular …

… look brighter following a recent report that the protective efficacy of a vaccine based on
circumsporozoite protein alone can be much enhanced by formulations designed to boost both …

… The RTS,S vaccine, the first malaria vaccine to be … protection in clinical trials [5], [6]. The
final results of the RTS,S phase 3 trial are an important landmark, but protective efficacy was …

… the association between HBsAg antibody titres and malaria vaccine efficacy in this study.
Analyses of the hazard of recurrent clinical malaria episodes attained optimal fitness per AIC …

… Malaria Vaccine Initiative (MVI) supports the development and testing of a number of malaria
vaccines that … Both JC and WRB are listed as the “inventors” of patented malaria vaccines. …

… The failure of RTS,S to induce CD8+ T-cell responses in humans may explain its lack of
sterile protective efficacy to malaria parasites, at least in the current regimens used in Phase 3 …

… of the synthetic malaria vaccine SPf66 … malaria vaccine is both safe and effective in a
preliminary clincal trial (clinical phase lib). The safety, tolerance and efficacy of the SPf66 vaccine …

… More importantly, the vaccine-elicited antibodies produced significant antiparasite activity …
of malaria. There is now a need to evaluate the protective efficacy of this malaria vaccine in …

… efficacy of the RTS,S/AS02A candidate malaria vaccine … into the mechanism of long lasting
protection, we have now … malaria and vaccine efficacy against clinical malaria in cohort 2. …

… It showed mild protective efficacy in a South American and a Tanzanian study, but failed to
show any benefit in the studies conducted in Gambia or Thailand. , 210 , 211 , 212 , 213 , 214 …