Malaria vaccine trials in a wormy world

M Nacher - Trends in parasitology, 2001 - cell.com
… of malaria vaccine trials is reassuring because this should avoid bias and confounding.
However, these trials do not … in malaria incidence or severity between the vaccinated and the non-…

[HTML][HTML] Advances and challenges in malaria vaccine development

PD Crompton, SK Pierce… - The Journal of clinical …, 2010 - Am Soc Clin Investig
… New vaccine targets need to be identified to improve the chances of developing a highly
effective malaria vaccine. … of malaria vaccines in field trials is assessed as the time to first clinical …

Malaria vaccine developments

VS Moorthy, MF Good, AVS Hill - The lancet, 2004 - thelancet.com
… in malaria vaccine development in the past 5 years: reasons for cautious optimism, the type
of vaccine that … occurred mainly in experimental models rather than in human vaccine trials. …

Correlating efficacy and immunogenicity in malaria vaccine trials

MBB McCall, PG Kremsner, B Mordmüller - Seminars in Immunology, 2018 - Elsevier
… in malaria vaccine development: Does immunogenicity predict malaria vaccine efficacy and
… Have immunological correlates accelerated malaria vaccine development in the past and …

Malaria vaccine trials in pregnant women: an imperative without precedent

SA Healy, M Fried, T Richie, K Bok, M Little, A August… - Vaccine, 2019 - Elsevier
… Pregnant women are highly susceptible to Plasmodium falciparum malaria, … malaria
vaccine development has made significant progress in recent years, no trials of malaria vaccines

Malaria vaccine clinical trials: what's on the horizon

A Moreno, C Joyner - Current opinion in immunology, 2015 - Elsevier
… vivax vaccine research requires more momentum and additional … vaccine candidates. In
this review, recently completed and ongoing malaria vaccine clinical trials as well as vaccine

Malaria vaccine trials

B Greenwood, P Alonso - Malaria Immunology, 2002 - karger.com
… 1) and many more trials of the safety and immunogenicity of malaria vaccines in volunteers
… of a field trial of a malaria vaccine in an endemic area, a study of a pre-erythrocytic vaccine

[HTML][HTML] A review of malaria vaccine clinical projects based on the WHO rainbow table

L Schwartz, GV Brown, B Genton, VS Moorthy - Malaria journal, 2012 - Springer
… the most advanced malaria vaccine, RTS,S/AS01, indicates that malaria vaccine R&D is
moving into a new phase. Field trials of several research malaria vaccines have also confirmed …

[HTML][HTML] The power of malaria vaccine trials using controlled human malaria infection

LE Coffeng, CC Hermsen, RW Sauerwein… - PLoS computational …, 2017 - journals.plos.org
… parasites, hepatic vaccine trials required significantly more study subjects than erythrocytic
vaccine trials. We provide power calculations for hypothetical malaria vaccine trials of various …

A field trial to assess a blood-stage malaria vaccine

MA Thera, OK Doumbo, D Coulibaly… - … England Journal of …, 2011 - Mass Medical Soc
trial, we immunized 400 Malian children with either the malaria vaccine or a control (rabies)
vaccine and … The primary end point was clinical malaria, defined as fever and at least 2500 …