Molecular targets for malarial chemotherapy: a review

DK Yadav, S Kumar, MK Teli, R Yadav… - Current topics in …, 2019 - ingentaconnect.com
… resistance; or by identifying novel targets for the malarial chemotherapy. In this review article,
… the novel molecular targets has been enlisted for the antimalarial drugs. The targets which …

Novel molecular targets for antimalarial chemotherapy

S Jana, J Paliwal - International journal of antimicrobial agents, 2007 - Elsevier
… development of effective new drugs against drug-resistant malaria strains. This review
discusses novel molecular targets of the malaria parasite available to the drug discovery scientist. …

[PDF][PDF] New targets in malaria parasite chemotherapy: a review

D Nigussie, T Beyene, NA Shah, S Belew - Malaria Contr Elimination, 2015 - academia.edu
… of novel targets in the development of new therapy. Therefore, this review will discuss …
targets in the chemotherapy of malaria parasite. Keywords: Malaria parasite Chemotherapy; …

An overview of chemotherapeutic targets for antimalarial drug discovery

PL Olliaro, Y Yuthavong - Pharmacology & therapeutics, 1999 - Elsevier
… Potential chemotherapeutic targets in the malaria parasite can be broadly classified into
three categories: those involved in processes occurring in the digestive vacuole, enzymes …

[HTML][HTML] The proteasome of malaria parasites: A multi-stage drug target for chemotherapeutic intervention?

MN Aminake, HD Arndt, G Pradel - International Journal for Parasitology …, 2012 - Elsevier
… as an antimalarial drug target, our understanding of protein regulation in malaria parasites
… to the requirements of the highly specialized malaria parasite. To reveal detailed function of …

Present trends and future strategy in chemotherapy of malaria

PMS Chauhan, SK Srivastava - Current medicinal chemistry, 2001 - ingentaconnect.com
… PLAUSIBLE BIOCHEMICAL TARGET SITES: Although numerous biochemical target sites
are known in malaria but this review complies only important targets which is needed to be …

Antimalarials: molecular drug targets and mechanism of action

AO Achieng, M Rawat, B Ogutu… - Current topics in …, 2017 - ingentaconnect.com
… Conclusion: This review summarizes current anti-malarialmolecular targets and mode
of action are discussed below. … As such, generation of drug resistance to the chemotypes …

Proteases of malaria parasites: new targets for chemotherapy.

PJ Rosenthal - Emerging infectious diseases, 1998 - ncbi.nlm.nih.gov
… Among potential targets for new modes of chemotherapy are malarial proteases, which
appear to mediate processes within the erythrocytic malarial life cycle, including the rupture and …

Current status and progresses made in malaria chemotherapy

GE Garcia Linares, JB Rodriguez - Current medicinal chemistry, 2007 - ingentaconnect.com
… analysis of selected molecular targets is depicted in terms of their potential utility as
chemotherapeutic agents. Our review focuses on different and important molecular targets for drug …

Recent developments and rationale towards new strategies for malarial chemotherapy

H Vial - Parasite, 1996 - parasite-journal.org
… A necessary first step is to identify a molecular target critical to the disease process;
infectious pathogens are particularly suited for the exploitation of divergent or completely novel …