… melanoma-… malignant melanoma cells and further activated by hypophosphorylation. Stable
antisense-HMG1 expression in melanoma cells led to the reduction of MIA promoter activity …

… Identification of Akt3 involvement in malignant melanoma. A, Akt activity in the melanoma
cell line UACC 903 is regulated by PTEN. Western blot analysis showing expression of …

… of melanoma inhibitory activity (MIA), an 11 kDa protein secreted from malignant melanoma
cells … Purified MIA confers growth inhibition to malignant melanoma cells in vitro and causes …

… tumors, high MIA mRNA levels were detected in almost 100% of malignant melanoma … ,
and malignant melanomas, we observed that MIA mRNA levels parallel progressive malignancy …

… Melanoma inhibitory activity (MIA) has been identified as a small protein secreted from malignant
melanoma cells. Recent … specifically with attachment of melanoma cells to fibronectin, a …

… cell growth-inhibiting activities were isolated from supernatants of a malignant melanoma
cell line, HTZ 19-dM, established from a central nervous system melanoma metastasis. HTZ 19-…

… Our assays demonstrated strong activity of the MAP kinases in the melanoma cell lines. …
p38 MAPK activity in melanoma cells, whereas erk1, erk2, and JNK activity remained unchanged…

… Purified MIA confers growth-inhibition to malignant melanoma cells in vitro and causes
significant alteration of cell morphology as melanoma cells round up. MIA activity was shown to …

… In addition, anti-tumour lymphokine-activated killer cell (LAK) … human melanoma cells
enhanced the autologous LAK-cell activity. … seen in malignant melanomas by inhibiting cellular …

… Malignant melanoma is one of the most aggressive skin … with antiproliferative and cytotoxic
activity on melanoma cells. We … capability to inhibit cell growth on primary melanoma cell lines …