… phorylated Pol II CTD primary structure … CTD by mammalian capping enzyme Mce, we
determined the crystal structure at a resolution of 2.8 Aof its GTase domain in complex with a CTD-…

… CTD code” that is read by capping enzyme independent of and parallel to its response to the
state of the Pol2 CTD. … ) and mammalian GTase (Mce1) bound to Ser5-phosphorylated Pol2 …

… will focus on the larger (17 aa) CTD interface with cap- … individual CTD side chains for capping
enzyme ping enzyme … each in other fungal and mammalian capping enzymes. This other. …

… C-terminal domain (CTD) of the … mammalian mRNA capping enzyme interacts directly with
pol IIO, the hyperphosphorylated form of pol II, but not with pol IIA, the form in which the CTD is …

… CTD code” hypothesizes that the sequential modifications of the CTD marks specify a
recognition code … of only consensus CTD repeats (52 repeats with YSPTSPS) in mammals shows …

… We expect that future structural studies of the mammalian GTase will confirm CTD binding
to … In order to characterize the differences in the GTase–CTD interaction as the CTD code is …

… Here, we describe an unexpected function for mammalian CE. Our findings arose from …
properties of the CTD. For these studies, we created a mouse CTD-T7 RNA polymerase (CTD-T7 …

… We expect that future structural studies of the mammalian GTase will confirm CTD binding
to … In order to characterise the differences in the GTase-CTD interaction as the CTD code is …

… mammalian cells, we have isolated and characterized cDNA clones that code for the human
and mouse capping enzymes. … with pol II containing a phosphorylated CTD, we propose that …

… In contrast with Cgt1, the mammalian capping enzyme MCE1 interacts with a short doubly
phosphorylated pS 5a P 6a S 7a Y 1b pS 2b P 3b peptide (Figure 7(b)). The peptide is …