… Cryptococcus neoformans, an encapsulated yeast saprophyte with global distribution,
has been recognized as an important emerging pathogen. Humans frequently develop …

… factors of C. neoformans. Therefore, virulence factor expression is to a large extent embedded
in the regulation of a variety of functions needed for growth in mammalian hosts. In this …

… how different Cryptococcus morphotypes exhibit different levels of pathogenicity in hosts are
… of each form inside and outside of mammalian hosts and summarizes recent insights on the …

… Virulence of Cryptococcus neoformans for mammals, and in particular its … mammalian
host are also important for survival within the amoeba. To better understand the origin of C…

… neoformans, which does not include a mammalian host in its normal life-cycle, has … that
are essential for microbial invasion of the mammalian host. However, direct exposure to high …

… immune responses to C. neoformans, with an emphasis on recent studies on the role of B
cells, natural IgM and Fc gamma receptor polymorphisms in resistance to cryptococcosis. …

… exchange factor) from Cryptococcus neoformans. These heterologous non-mammalian
hosts highlight the similarities and differences between different hosts in fungal pathogenesis …

… Infection occurs when spores and/or dissected yeasts are inhaled by human or mammalian
hosts. In the lung, the inhaled fungi are deposited into the alveoli and establish a latent …

… neoformans cells were not killed by amoebae. These observations established that C.
neoformans virulence factors in mammalian hosts were also virulence factors in amoebae. …

… roles of alveolar macrophages in the host response to Cryptococcus neoformans. J. Infect. …
-inhibitory mechanisms in mammalian infection by Cryptococcus neoformans. Cell …