… that drive aerobic glycolysis have been … the retina. Here, we review recent research on the
molecular mechanisms that underly aerobic glycolysis in the retina, focusing on key glycolytic …

… His team also noted that normal mammalian retinal explants displayed aerobic glycolysis.4 …
Several decades thereafter, other researchers confirmed that the mammalian retina indeed …

… Studies in the retina show that aerobic glycolysis is essential for retinal cell survival. Although
photoreceptors are post-mitotic, PKM2 is the predominant isoform in these cells. In tumor …

… Photoreceptors and Müller cells were therefore both of particular focus in this project due
to their proposed roles in retinal aerobic glycolysis, so these cell types are reviewed in detail …

… Rod and cone photoreceptors (PRs) are the neurons ensuring light detection in the retina. …
Among the four mammalian HK isoenzymes, HK1 is the most ubiquitously expressed HK ( …

… glycolysis or respiration. One approach to this problem is to determine whether the mammalian
retina … The support of Fast PIII by anaerobic glycolysis with 20 mM glucose is paralleled …

… to supply the retina, while other mammals rely solely on the choroid at the cost of retinal
thickness. … There are many mysteries regarding glycolysis and lactate production in the retina, …

… in the retina, which play a central role in the vision process. Light photons are detected by
the photoreceptors and processed into electrical signals in the retina. In mammals, rods are …

… rabbit, and rat retinas revealed the retina’s capacity for aerobic glycolysis (the Warburg
effect… that glycolysis and OXPHOS were differentially distributed in the adult mammalian retina. …

… retinal explants produce large amounts of lactate even under aerobic conditions; this is termed
aerobic glycolysis… for the majority of glycolysis in the mammalian retina. This is supported …